back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+

PR:000044465 - http://purl.obolibrary.org/obo/PR_000044465
Ontology Information
PRO ID PR:000044465 Show OBO stanza / PAF / GPI
PRO name CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse)
Synonyms
PRO-short-label: EXACT: mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+
PRO-proteoform-std: EXACT: UniProtKB:P31809-2, 35-458, MOD:00160
Other: EXACT: Ceacam1a isoform Short glycosylated (mouse)
RELATED: Bgp A glycosylated (mouse) | Bgp1/4S glycosylated (mouse) | Ceacam1/D1-4S glycosylated (mouse) | mmCGM1a glycosylated (mouse)
Definition A carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form that is the signal cleavage product of isoform Short in mouse and includes at least one N-glycosylasparagine. UniProtKB:P31809-2, 35-458, MOD:00160. [PMID:11483763, PMID:1648219, PMID:2164599, PMID:8896983, PRO:KRC, UniProtKB:P31809]
Comment Evidence=(ECO:0000250, based on PMID:2164599). Note: PMID:1648219 and PMID:2164599 shows sequencing of mature N-terminus of Ceacam1 purified from Swiss Webster mice, but not specific to a sequence isoform; PMID:8896983 shows immunoblot showing native size of purified BgpA (Bgp1/4S) and BgpD (Bgp1/2S) and after N-glycanase treatment (Fig 2A).
PRO Category organism-modification
Parent PR:000018399 carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044465
mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+
MOD:00160
acts_upstream_of_or_within GO:0048541 Peyer's patch development MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:0042102 positive regulation of T cell proliferation MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:0046718 viral entry into host cell MGI:49235, PMID:1719235
acts_upstream_of_or_within GO:0070886 positive regulation of calcineurin-NFAT signaling cascade MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:0070237 positive regulation of activation-induced cell death of T cells MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:0002639 positive regulation of immunoglobulin production MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation MGI:5451119, PMID:23123061
acts_upstream_of_or_within GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules MGI:5608586, PMID:1633107
enables GO:0046790 virion binding MGI:3053174, PMID:8380065
enables GO:0001618 virus receptor activity MGI:49235, PMID:1719235
located_in GO:0009897 external side of plasma membrane MGI:81180, PMID:8896983
located_in GO:0009897 external side of plasma membrane MGI:5608586, PMID:1633107
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009897 external side of plasma membrane PR:000044465 mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+
MOD:00160
MGI:81180, PMID:8896983
PR:000044465 mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+
MOD:00160
MGI:5608586, PMID:1633107

top