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Protein Ontology Report - mCEACAM1a/iso:2/SigPep-/NGlycoAsn+

PR:000044471 - http://purl.obolibrary.org/obo/PR_000044471
Ontology Information
PRO ID PR:000044471 Show OBO stanza / PAF / GPI
PRO name CEACAM1a-2, signal peptide removed N-glycosylasparagine form (mouse)
Synonyms
PRO-short-label: EXACT: mCEACAM1a/iso:2/SigPep-/NGlycoAsn+
PRO-proteoform-std: EXACT: UniProtKB:Q3LFS7, 35-236, MOD:00160
Definition A carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form that is the signal cleavage product of isoform CEACAM1a-2 of allele CEACAM1a in mouse and includes at least one N-glycosylasparagine. UniProtKB:Q3LFS7, 35-236, MOD:00160. [PMID:19358828, PRO:KRC]
Comment Evidence=(ECO:0000006, based on PMID:19358828). Note: PMID:19358828 in figure 2B shows in vitro expression of Ceacam1a-2, Ceacam1a-2C1 and Ceacam1a-4C1 isoforms by BHK transfectants followed by immunoprecipitation and Western blotting detects these Ceacam1 isoforms at approximately 55, 45, and 120 kDa, respectively. While the authors do not explicitly mention glycosylation, these sizes are consistent with weights of glycosylated forms and not with predicted weights of unmodified isoforms.
PRO Category organism-modification
Parent PR:000018399 carcinoembryonic antigen-related cell adhesion molecule 1, signal peptide removed form
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044471
mCEACAM1a/iso:2/SigPep-/NGlycoAsn+
MOD:00160
located_in GO:0005615 extracellular space MGI:3848729, PMID:19358828
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005615 extracellular space PR:000044471 mCEACAM1a/iso:2/SigPep-/NGlycoAsn+
MOD:00160
MGI:3848729, PMID:19358828

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