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Protein Ontology Report - hCDKN1B/iso:1/UnPhos:2

PR:000045370 - http://purl.obolibrary.org/obo/PR_000045370
Ontology Information
PRO ID PR:000045370 Show OBO stanza / PAF
PRO name cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human)
Synonyms
PRO-short-label: hCDKN1B/iso:1/UnPhos:2
PRO-proteoform-std: UniProtKB:P46527-1, Tyr-88, PR:000026291
Definition A cyclin-dependent kinase inhibitor 1B isoform 1 (human) that lacks phosphorylation at Tyr-88. UniProtKB:P46527-1, Tyr-88, PR:000026291. [PRO:CNA]
PRO Category organism-modification
Parent PR:P46527-1 cyclin-dependent kinase inhibitor 1B isoform 1 (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000045370
hCDKN1B/iso:1/UnPhos:2
Tyr-88, PR:000026291
capable_of GO:0044877 protein-containing complex binding with PR:000026741 cyclin D1:Cdk4 (human) PMID:17254966
capable_of GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PMID:17254966
capable_of GO:0005515 protein binding with PR:P31749 hAKT1 PMID:12244301
located_in GO:0005634 nucleus PMID:12244301
participates_in GO:0008285 negative regulation of cell population proliferation PMID:12244301
participates_in GO:0051318 G1 phase PMID:17254966
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0008285 negative regulation of cell population proliferation PR:000045370 hCDKN1B/iso:1/UnPhos:2
Tyr-88, PR:000026291
PMID:12244301
GO:0051318 G1 phase PR:000045370 hCDKN1B/iso:1/UnPhos:2
Tyr-88, PR:000026291
PMID:17254966
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000045370 hCDKN1B/iso:1/UnPhos:2
Tyr-88, PR:000026291
PMID:12244301

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