Protein Ontology Report - hIgA1/circulating PR:000050159 - http://purl.obolibrary.org/obo/PR_000050159

Ontology Information
PRO ID	PR:000050159 Show OBO stanza / GPI
PRO name	IgA1 immunoglobulin complex, circulating (human)
Synonyms	PRO-short-label: EXACT: hIgA1/circulating Other: EXACT: IgA1 antibody (human) BROAD: IgA antibody (human)
Definition	An IgA immunoglobulin complex, circulating that in monomeric form is composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment	Requested by=HIPC.Requested by=CL.
PRO Category	organism-complex
Parent	GO:0071746 IgA immunoglobulin complex, circulating
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-complex 6
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000050159 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] PR:000050376 IgA1 heavy chain protein, secretory isoform (human) hIgHA1/iso:secretory An IgA1 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA1 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA. [GOC:add, PRO:ADD, PRO:DAN] PR:000050163 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2 PR:000050376 IgA1 heavy chain protein, secretory isoform (human) hIgHA1/iso:secretory An IgA1 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA1 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA. [GOC:add, PRO:ADD, PRO:DAN] 2

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