An IgA immunoglobulin complex, circulating that in monomeric form is composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
[GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment
Requested by=HIPC.Requested by=CL.
PRO Category
organism-complex
Parent
GO:0071746 IgA immunoglobulin complex, circulating
IgA1 heavy chain protein, secretory isoform (human)
hIgHA1/iso:secretory
An IgA1 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA1 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA.
[GOC:add, PRO:ADD, PRO:DAN]
IgA1 heavy chain protein, secretory isoform (human)
hIgHA1/iso:secretory
An IgA1 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA1 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA.
[GOC:add, PRO:ADD, PRO:DAN]