IgA antibody (human) | monomeric IgA antibody (human)
Definition
An IgA immunoglobulin complex, circulating composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA2 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
[GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment
Requested by=HIPC. Requested by=CL. Note: Human circulating IgA2 is only found as a monomeric form.
PRO Category
organism-complex
Parent
GO:0071746 IgA immunoglobulin complex, circulating
IgA2 heavy chain protein, secretory isoform (human)
hIgHA2/iso:secretory
An IgA2 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA2 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA.
[GOC:add, PRO:ADD, PRO:DAN]
DAG
OLS
Cytoscape