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Protein Ontology Report - hIgA2/circulating

PR:000050160 -
Ontology Information
PRO ID PR:000050160 Show OBO stanza / GPI
PRO name IgA2 immunoglobulin complex, circulating (human)
PRO-short-label: EXACT: hIgA2/circulating
Other: EXACT: IgA2 antibody (human) | monomeric IgA2 antibody (human) | monomeric IgA2 immunoglobulin complex (human)
BROAD: IgA antibody (human) | monomeric IgA antibody (human)
Definition An IgA immunoglobulin complex, circulating composed of two identical immunoglobulin heavy chains of the secretory isoform of the IgA2 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment Requested by=HIPC. Requested by=CL. Note: Human circulating IgA2 is only found as a monomeric form.
PRO Category organism-complex
Parent GO:0071746 IgA immunoglobulin complex, circulating
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000050160 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050378 IgA2 heavy chain protein, secretory isoform (human) hIgHA2/iso:secretory An IgA2 heavy chain protein, secretory isoform that is encoded in the genome of human. This is a translation product of an IgA2 mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA. [GOC:add, PRO:ADD, PRO:DAN] 2