Protein Ontology Report - h(IgA1)dimeric PR:000050166 - http://purl.obolibrary.org/obo/PR_000050166

Ontology Information
PRO ID	PR:000050166 Show OBO stanza / GPI
PRO name	dimeric IgA1 immunoglobulin complex (human)
Synonyms	PRO-short-label: EXACT: h(IgA1)dimeric Other: EXACT: dimeric IgA1 antibody (human) BROAD: dimeric IgA antibody (human)
Definition	A polymeric IgA1 immunoglobulin complex (human) that is composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA1 monomer consists of two identical immunoglobulin heavy chains of the secretory isoform of the IgA isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. Dimeric IgA1 is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment	Requested by=HIPC. Requested by=CL. Dimeric IgA1 is by far the most common form of polymeric IgA1. In human only the IgA1 isotype is capable of a dimeric form.
PRO Category	organism-complex
Parent	PR:000050165 polymeric IgA1 immunoglobulin complex (human)
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-complex 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex

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