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Protein Ontology Report - h(IgA1/secretory)polymeric

PR:000050167 - http://purl.obolibrary.org/obo/PR_000050167
Ontology Information
PRO ID PR:000050167 Show OBO stanza / GPI
PRO name secretory polymeric IgA1 immunoglobulin complex (human)
Synonyms
PRO-short-label: EXACT: h(IgA1/secretory)polymeric
Other: EXACT: sIgA1 antibody (human) | secretory IgA1 antibody (human)
BROAD: sIgA antibody (human) | secretory IgA antibody (human)
Definition A polymeric IgA1 immunoglobulin complex (human) that is complexed with one chain of secretory component (SC). Polymeric IgA1 is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment Requested by=HIPC. Requested by=CL. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.
PRO Category organism-complex
Parent PR:000050165 polymeric IgA1 immunoglobulin complex (human)
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex


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