sIgA antibody (human) | secretory IgA antibody (human)
A polymeric IgA1 immunoglobulin complex (human) that is complexed with one chain of secretory component (SC). Polymeric IgA1 is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.
[GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Requested by=HIPC. Requested by=CL. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA.