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Protein Ontology Report - hIgG1

PR:000050305 - http://purl.obolibrary.org/obo/PR_000050305
Ontology Information
PRO ID PR:000050305 Show OBO stanza / GPI
PRO name IgG1 immunoglobulin complex (human)
Synonyms
PRO-short-label: EXACT: hIgG1
Other: EXACT: IgG1 (human)
NARROW: IgG1 antibody (human)
BROAD: IgG (human)
Definition An IgG immunoglobulin complex that is composed of two identical immunoglobulin heavy chains of an IgG1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG1 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, PMID:25368619, PRO:ADD]
Comment Requested by=HIPC. Requested by=CL. Note: An IgG1 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
PRO Category organism-complex
Parent GO:0071735 IgG immunoglobulin complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 3
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000050313 PR:P40259 B-cell antigen receptor complex-associated protein beta chain (human) hCD79B A B-cell antigen receptor complex-associated protein beta chain that is encoded in the genome of human. [PRO:WCB, UniProtKB:P40259] 1
PR:P11912 B-cell antigen receptor complex-associated protein alpha chain (human) hCD79A A B-cell antigen receptor complex-associated protein alpha chain that is encoded in the genome of human. [PRO:WCB, UniProtKB:P11912] 1
PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050301 IgG1 heavy chain protein, membrane-bound isoform (human) hIgHG1/iso:membrane-bound An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons. [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN] 2
PR:000050305 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050291 IgG1 heavy chain protein (human) hIgHG1 An IgG1 heavy chain protein that is encoded in the genome of human. [GOC:add, PRO:ADD, PRO:DAN] 2
PR:000050309 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050297 IgG1 heavy chain protein, secretory isoform (human) hIgHG1/iso:secretory An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA. [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN] 2


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