An IgG immunoglobulin complex that is composed of two identical immunoglobulin heavy chains of an IgG1 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG1 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
[GOC:add, PMID:25368619, PRO:ADD]
Requested by=HIPC. Requested by=CL. Note: An IgG1 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
IgG1 heavy chain protein, secretory isoform (human)
An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA.
[GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]