Protein Ontology Report - hIgG1/circulating PR:000050309 - http://purl.obolibrary.org/obo/PR_000050309

Ontology Information
PRO ID	PR:000050309 Show OBO stanza / GPI
PRO name	IgG1 immunoglobulin complex, circulating (human)
Synonyms	PRO-short-label: EXACT: hIgG1/circulating Other: EXACT: IgG1 antibody (human) BROAD: IgG antibody (human)
Definition	An IgG1 immunoglobulin complex (human) that is composed of two identical immunoglobulin heavy chains of an IgG1 isotype of the secretory isoform and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, PMID:25368619, PRO:ADD]
Comment	Requested by=HIPC.Requested by=CL.
PRO Category	organism-complex
Parent	PR:000050305 IgG1 immunoglobulin complex (human)
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-complex 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Complex Forms Display Category: All All organism-complex
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits

Complex PRO ID Name Short Label Definition Number in Complex PR:000050309 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2 PR:000050297 IgG1 heavy chain protein, secretory isoform (human) hIgHG1/iso:secretory An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA. [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN] 2

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