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Protein Ontology Report - hIgG3/B-cell-receptor

PR:000050315 - http://purl.obolibrary.org/obo/PR_000050315
Ontology Information
PRO ID PR:000050315 Show OBO stanza
PRO name IgG3 B cell receptor complex (human)
Synonyms
PRO-short-label: EXACT: hIgG3/B-cell-receptor
Other: EXACT: membrane-bound IgG3 (human) | surface IgG3 (human)
BROAD: membrane-bound IgG (human) | surface IgG (human)
Definition An IgG3 immunoglobulin complex (human) that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the membrane-bound isoform of the IgG3 isotype, two identical immunoglobulin light chains (kappa or lambda), and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. [GOC:add, ISBN:0781765196, PMID:17496345, PRO:ADD]
Comment Requested by=HIPC.Requested by=CL.
PRO Category organism-complex
Parent PR:000050307 IgG3 immunoglobulin complex (human)
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000050315 PR:P40259 B-cell antigen receptor complex-associated protein beta chain (human) hCD79B A B-cell antigen receptor complex-associated protein beta chain that is encoded in the genome of human. [PRO:WCB, UniProtKB:P40259] 1
PR:P11912 B-cell antigen receptor complex-associated protein alpha chain (human) hCD79A A B-cell antigen receptor complex-associated protein alpha chain that is encoded in the genome of human. [PRO:WCB, UniProtKB:P11912] 1
PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050303 IgG3 heavy chain protein, membrane-bound isoform (human) hIgHG3/iso:membrane-bound An IgG3 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons. [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN] 2


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