Protein Ontology Report - hLEFTY2 PR:O00292 - http://purl.obolibrary.org/obo/PR_O00292

This page represents a class of proteins encompassing all the protein products of the LEFTY2 gene in Homo sapiens.

Ontology Information
PRO ID	PR:O00292 Show OBO stanza / PAF / GPI
PRO name	left-right determination factor 2 (human)
Synonyms	PRO-short-label: EXACT: hLEFTY2 Gene-based: RELATED: EBAF | LEFTA | LEFTY2 | LEFTYA | PSEC0024 | TGFB4 Other: EXACT: TGF-beta-4 (human) | endometrial bleeding-associated factor (human) | left-right determination factor A (human) | protein lefty-2 (human) | protein lefty-A (human) | transforming growth factor beta-4 (human)
Definition	A lefty 2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:O00292]
PRO Category	organism-gene
Parent	PR:000000288 lefty 2
Gene Template	HGNC:3122 LEFTY2
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 3
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:O00292

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000000452 hLEFTY2/var:S342N Ser-342, CHEBI:50347 associated_with_disease_progression DOID:0050545 visceral heterotaxy PMID:10053005 PR:O00292-1 hLEFTY2/iso:1 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:10053005 acts_upstream_of_or_within GO:0007309 oocyte axis specification PMID:10053005 PR:000036549 hLEFTY2/iso:1/Clv:1 acts_upstream_of_or_within GO:0007309 oocyte axis specification PMID:10053005 acts_upstream_of_or_within GO:0007275 multicellular organism development PMID:10053005 located_in GO:0005615 extracellular space PMID:11278322 PR:000036550 hLEFTY2/iso:1/Clv:2 acts_upstream_of_or_within GO:0043406 positive regulation of MAP kinase activity PMID:11278322 located_in GO:0005615 extracellular space PMID:11278322 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005615 extracellular space PR:000036549 hLEFTY2/iso:1/Clv:1 PMID:11278322 PR:000036550 hLEFTY2/iso:1/Clv:2 PMID:11278322

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