Protein Ontology Report - hBUB3 PR:O43684 - http://purl.obolibrary.org/obo/PR_O43684

This page represents a class of proteins encompassing all the protein products of the BUB3 gene in Homo sapiens.

Ontology Information
PRO ID	PR:O43684 Show OBO stanza / PAF / GPI
PRO name	mitotic checkpoint protein BUB3 (human)
Synonyms	PRO-short-label: EXACT: hBUB3 Gene-based: RELATED: BUB3
Definition	A mitotic checkpoint protein BUB3 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O43684]
PRO Category	organism-gene
Parent	PR:000004856 mitotic checkpoint protein BUB3
Gene Template	HGNC:1151 BUB3
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 3
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-141416, UniProtKB:O43684

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hBUB3 forms found in complexes
hBUB3 Component Complexes PR:O43684 hBUB3 PR:000035576 BUB1:BUB3:APC complex (human) PR:O43684 hBUB3 PR:000035567 BUB1:BUB3:MAD1L1 complex (human) PR:O43684 hBUB3 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human) PR:O43684 hBUB3 PR:000035563 BUB1B:BUB3 complex (human) PR:O43684 hBUB3 PR:000035564 BUB1:BUB3 complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035437 hBUB3/Phos:1 Ser-18, MOD:00046 acts_upstream_of_or_within GO:0012501 programmed cell death increased relative to PR:000035454 hBUB3/PhosRes- PMID:20057499 PR:O43684 hBUB3 enables GO:0005515 protein binding with PR:Q9Y6D9 hMAD1L1 PMID:10198256 enables GO:0005515 protein binding with PR:O15350-1 hTP73/iso:1 PMID:20057499 enables GO:0005515 protein binding with PR:Q12834 hCDC20 BioGRID:BG-561804, MINT:MINT-8183848 enables GO:0005515 protein binding with PR:O15350-5 hTP73/iso:5 PMID:20057499 enables GO:0005515 protein binding with PR:O15350-3 hTP73/iso:3 PMID:20057499 enables GO:0005515 protein binding with PR:P25054 hAPC BioGRID:BG-302961 enables GO:0005515 protein binding with PR:Q13257 hMAD2L1 BioGRID:BG-718926 enables GO:0005515 protein binding with PR:O43683 hBUB1 PMID:10198256 enables GO:0005515 protein binding with PR:O15350-2 hTP73/iso:2 PMID:20057499 enables GO:0005515 protein binding with PR:O60566 hBUB1B PMID:17785528 located_in GO:0000776 kinetochore PMID:11283619 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000776 kinetochore PR:O43684 hBUB3 PMID:11283619

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