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Protein Ontology Report - hLMNA

PR:P02545 - http://purl.obolibrary.org/obo/PR_P02545
This page represents a class of proteins encompassing all the protein products of the LMNA gene in human.
Ontology Information
PRO ID PR:P02545 Show OBO stanza / PAF
PRO name prelamin-A/C (human)
Synonyms
PRO-short-label: EXACT: hLMNA
Gene-based: RELATED: LMN1 | LMNA
Definition A prelamin-A/C that is encoded in the genome of human. [PRO:DNx, UniProtKB:P02545]
PRO Category organism-gene
Parent PR:000009859 prelamin-A/C
Gene Template HGNC:6636 LMNA
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 6
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P02545-2
hLMNA/iso:C
acts_upstream_of_or_within GO:0007517 muscle organ development PMID:10080180
enables GO:0005515 protein binding with PR:O60238 hBNIP3L PMID:10381623
enables GO:0005198 structural molecule activity PMID:3453101
enables GO:0005515 protein binding with PR:P03247-1 E1B/small-T (ADE02) PMID:10381623
enables GO:0005198 structural molecule activity PMID:8344919
located_in GO:0005635 nuclear envelope PMID:3453101
located_in GO:0005882 intermediate filament PMID:8344919
located_in GO:0005638 lamin filament PMID:10080180
located_in GO:0005652 nuclear lamina PMID:8344919
located_in GO:0048471 perinuclear region of cytoplasm PMID:10080180
PR:P02545-1
hLMNA/iso:A
acts_upstream_of_or_within GO:0007517 muscle organ development PMID:10080180
enables GO:0005198 structural molecule activity PMID:8344919
enables GO:0005515 protein binding with PR:P03247-1 E1B/small-T (ADE02) PMID:10381623
enables GO:0005198 structural molecule activity PMID:3453101
located_in GO:0005652 nuclear lamina PMID:8344919
located_in GO:0005638 lamin filament PMID:10080180
located_in GO:0048471 perinuclear region of cytoplasm PMID:10080180
located_in GO:0005882 intermediate filament PMID:8344919
located_in GO:0005635 nuclear envelope PMID:3453101
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005882 intermediate filament PR:P02545-1 hLMNA/iso:A

PMID:8344919
PR:P02545-2 hLMNA/iso:C

PMID:8344919
GO:0048471 perinuclear region of cytoplasm PR:P02545-1 hLMNA/iso:A

PMID:10080180
PR:P02545-2 hLMNA/iso:C

PMID:10080180
GO:0005638 lamin filament PR:P02545-1 hLMNA/iso:A

PMID:10080180
PR:P02545-2 hLMNA/iso:C

PMID:10080180
GO:0005652 nuclear lamina PR:P02545-1 hLMNA/iso:A

PMID:8344919
PR:P02545-2 hLMNA/iso:C

PMID:8344919
GO:0005635 nuclear envelope PR:P02545-1 hLMNA/iso:A

PMID:3453101
PR:P02545-2 hLMNA/iso:C

PMID:3453101

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