back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - hESR1

PR:P03372 - http://purl.obolibrary.org/obo/PR_P03372
This page represents a class of proteins encompassing all the protein products of the ESR1 gene in Homo sapiens.
Ontology Information
PRO ID PR:P03372 Show OBO stanza / PAF / GPI
PRO name estrogen receptor (human)
Synonyms
PRO-short-label: EXACT: hESR1
Gene-based: RELATED: ESR | ESR1 | NR3A1
Other: EXACT: ER (human) | ER-alpha (human) | estradiol receptor (human) | nuclear receptor subfamily 3 group A member 1 (human)
Definition An estrogen receptor that is encoded in the genome of human. [PRO:DNx, UniProtKB:P03372]
PRO Category organism-gene
Parent PR:000007204 estrogen receptor
Gene Template HGNC:3467 ESR1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 4
organism-modification 7
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000027726
hESR1/iso:1/Phos:2
Tyr-52/Tyr-219, MOD:00048
acts_upstream_of_or_within GO:0010628 positive regulation of gene expression PMID:20101225
enables GO:0042803 protein homodimerization activity PMID:20101225
located_in GO:0005634 nucleus PMID:20101225
PR:000027756
hESR1/iso:1/Ac:1
Lys-266/Lys-268, MOD:00064
enables GO:0003677 DNA binding PMID:16497729
PR:000027724
hESR1/iso:1/Phos:1
Ser-167, MOD:00046
acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:19940156
PR:000027776
hESR1/iso:1/Phos:4
Thr-311, MOD:00047
acts_upstream_of_or_within GO:0010628 positive regulation of gene expression PMID:12138194
located_in GO:0005634 nucleus PMID:12138194
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000027726 hESR1/iso:1/Phos:2
Tyr-52/Tyr-219, MOD:00048
PMID:20101225
PR:000027776 hESR1/iso:1/Phos:4
Thr-311, MOD:00047
PMID:12138194

top