Protein Ontology Report - hRAF1 PR:P04049 - http://purl.obolibrary.org/obo/PR_P04049

This page represents a class of proteins encompassing all the protein products of the RAF1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:P04049 Show OBO stanza / PAF / GPI
PRO name	RAF proto-oncogene serine/threonine-protein kinase (human)
Synonyms	PRO-short-label: EXACT: hRAF1 Gene-based: RELATED: RAF | RAF1 Other: EXACT: Raf-1 (human) | cRaf (human) | proto-oncogene c-RAF (human)
Definition	A RAF proto-oncogene serine/threonine-protein kinase that is encoded in the genome of human. [PMID:20703093, PRO:KER]
PRO Category	organism-gene
Parent	PR:000003244 RAF proto-oncogene serine/threonine-protein kinase
Gene Template	HGNC:9829 RAF1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 10
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100445, Reactome:R-HSA-167205, UniProtKB:P04049

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000036643 hRAF1/iso:1/Phos:2 Ser-338/Ser-339, MOD:00046 acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:15849194 enables GO:0004674 protein serine/threonine kinase activity PMID:15849194 enables GO:0005515 protein binding with PR:P10415 hBCL2 PMID:15849194 located_in GO:0005741 mitochondrial outer membrane PMID:15849194 PR:P04049 hRAF1 acts_upstream_of_or_within GO:0032877 positive regulation of DNA endoreduplication PMID:20703093 enables GO:0005515 protein binding with PR:O60566 hBUB1B PMID:20703093 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005741 mitochondrial outer membrane PR:000036643 hRAF1/iso:1/Phos:2 Ser-338/Ser-339, MOD:00046 PMID:15849194

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