back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - hTHBS1

PR:P07996 - http://purl.obolibrary.org/obo/PR_P07996
This page represents a class of proteins encompassing all the protein products of the THBS1 gene in Homo sapiens.
Ontology Information
PRO ID PR:P07996 Show OBO stanza / PAF / GPI
PRO name thrombospondin-1 (human)
Synonyms
PRO-short-label: EXACT: hTHBS1
Gene-based: RELATED: THBS1 | TSP | TSP1
Other: EXACT: glycoprotein G (human)
Definition A thrombospondin-1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:P07996]
PRO Category organism-gene
Parent PR:000000129 thrombospondin-1
Gene Template HGNC:11785 THBS1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 10
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hTHBS1 forms found in complexes
hTHBS1 Component Complexes
PR:000028410 hTHBS1/SigPep- PR:000028445 integrin alphaIIbbeta3:thrombospondin 1 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000028410
hTHBS1/SigPep-
located_in GO:0005615 extracellular space PMID:15662972
PR:000000129
THBS1
acts_upstream_of_or_within GO:0007596 blood coagulation PANTHER:PTHR10199:SF37
PR:000026338
hTHBS1/iso:1/SigPep-
enables GO:0004866 endopeptidase inhibitor activity PMID:8751720
located_in GO:0005615 extracellular space PMID:15662972
PR:000036488
hTHBS1/iso:1/SigPep-/Glyco:1
Trp-385/Trp-438/Trp-441/Trp-498, MOD:00222|Ser-394, MOD:00812|Thr-450/Thr-507, MOD:00813
enables GO:0005515 protein binding with PR:000028966 hTHBS1/iso:1/Clv:2 PMID:3305519
enables GO:0050431 transforming growth factor beta binding PMID:15342643
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005615 extracellular space PR:000026338 hTHBS1/iso:1/SigPep-

PMID:15662972
PR:000028410 hTHBS1/SigPep-

PMID:15662972

top