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Protein Ontology Report - hSP1

PR:P08047 - http://purl.obolibrary.org/obo/PR_P08047
This page represents a class of proteins encompassing all the protein products of the SP1 gene in human.
Ontology Information
PRO ID PR:P08047 Show OBO stanza / PAF
PRO name transcription factor Sp1 (human)
Synonyms
PRO-short-label: EXACT: hSP1
Gene-based: RELATED: SP1 | TSFP1
Definition A transcription factor Sp1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:P08047]
PRO Category organism-gene
Parent PR:000000133 transcription factor Sp1
Gene Template HGNC:11205 SP1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 3
organism-modification 11
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000036496
hSP1/iso:1/Ac:1
acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15647279
enables GO:0003677 DNA binding PMID:15647279
located_in GO:0005634 nucleus PMID:15647279
PR:000036497
hSP1/iso:1/Clv:1
enables GO:0003700 DNA-binding transcription factor activity PMID:16407261
located_in GO:0005634 nucleus PMID:16407261
PR:000036500
hSP1/iso:1/Phos:2
Thr-579, MOD:00047
enables GO:0003700 DNA-binding transcription factor activity decreased relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:9153193
located_in GO:0005634 nucleus PMID:9153193
PR:000036501
hSP1/iso:1/Phos:3
Ser-59, MOD:00046
enables GO:0003700 DNA-binding transcription factor activity increased relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:17049555, PMID:18239466
located_in GO:0005634 nucleus PMID:17049555, PMID:18239466
PR:000036502
hSP1/iso:1/Phos:4
acts_upstream_of_or_within GO:0006975 DNA damage induced protein phosphorylation PMID:18171990
located_in GO:0005634 nucleus PMID:18171990
PR:000036503
hSP1/iso:1/Sumo:1
Lys-16, MOD:01149
enables GO:0003700 DNA-binding transcription factor activity decreased relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:16407261
PR:P08047-1
hSP1/iso:1
located_in GO:0005634 nucleus PMID:2170018
PR:000036498
hSP1/iso:1/OGlyco:1
Ser-491, MOD:00805
enables GO:0003700 DNA-binding transcription factor activity increased relative to PR:000036497 hSP1/iso:1/Clv:1 PMID:11371615
enables GO:0003677 DNA binding PMID:11371615
located_in GO:0005634 nucleus PMID:11371615
PR:000036499
hSP1/iso:1/Phos:1
enables GO:0003677 DNA binding PMID:2170018
located_in GO:0005634 nucleus PMID:2170018, PMID:9525578
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000036496 hSP1/iso:1/Ac:1

PMID:15647279
PR:000036497 hSP1/iso:1/Clv:1

PMID:16407261
PR:000036498 hSP1/iso:1/OGlyco:1
Ser-491, MOD:00805
PMID:11371615
PR:000036499 hSP1/iso:1/Phos:1

PMID:2170018, PMID:9525578
PR:000036500 hSP1/iso:1/Phos:2
Thr-579, MOD:00047
PMID:9153193
PR:000036501 hSP1/iso:1/Phos:3
Ser-59, MOD:00046
PMID:17049555, PMID:18239466
PR:000036502 hSP1/iso:1/Phos:4

PMID:18171990
PR:P08047-1 hSP1/iso:1

PMID:2170018

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