Protein Ontology Report - hCFTR PR:P13569 - http://purl.obolibrary.org/obo/PR_P13569

This page represents a class of proteins encompassing all the protein products of the CFTR gene in Homo sapiens.

Ontology Information
PRO ID	PR:P13569 Show OBO stanza / PAF / GPI
PRO name	cystic fibrosis transmembrane conductance regulator (human)
Synonyms	PRO-short-label: EXACT: hCFTR Gene-based: RELATED: ABCC7 | CFTR Other: EXACT: ATP-binding cassette sub-family C member 7 (human) | cAMP-dependent chloride channel (human) | channel conductance-controlling ATPase (human)
Definition	A cystic fibrosis transmembrane conductance regulator that is encoded in the genome of human. [PRO:CNA, UniProtKB:P13569]
PRO Category	organism-gene
Parent	PR:000001044 cystic fibrosis transmembrane conductance regulator
Gene Template	HGNC:1884 CFTR
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:01100064, Reactome:R-HSA-383188, Reactome:R-HSA-5627079, Reactome:R-HSA-5627279, Reactome:R-HSA-6782965, Reactome:R-HSA-8866837, Reactome:R-HSA-8868730, UniProtKB:P13569

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:P13569-3 hCFTR/iso:3 associated_with_disease_progression DOID:1485 cystic fibrosis PMID:12913074 PR:000036594 hCFTR/iso:1/Phos:1 Ser-737/Ser-768/Ser-795/Ser-813, MOD:00046 enables GO:0005260 intracellularly ATP-gated chloride channel activity PMID:14602047 enables GO:0005260 intracellularly ATP-gated chloride channel activity PMID:1716180

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