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Protein Ontology Report - hCCND1

PR:P24385 -
This page represents a class of proteins encompassing all the protein products of the CCND1 gene in Homo sapiens.
Ontology Information
PRO ID PR:P24385 Show OBO stanza / PAF / GPI
PRO name G1/S-specific cyclin-D1 (human)
PRO-short-label: EXACT: hCCND1
Gene-based: RELATED: BCL1 | CCND1 | PRAD1
Other: EXACT: B-cell lymphoma 1 protein (human) | BCL-1 (human) | BCL-1 oncogene (human) | PRAD1 oncogene (human)
Definition A G1/S-specific cyclin-D1 that is encoded in the genome of human. [PRO:DNx]
PRO Category organism-gene
Parent PR:000005121 G1/S-specific cyclin-D1
Gene Template HGNC:1582 CCND1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 3
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCCND1 forms found in complexes
hCCND1 Component Complexes
PR:000005121 CCND1 PR:000026740 cyclin D1:Cdk4
PR:000027132 hCCND1/Phos:1 PR:000027150 cyclin D1:Cdk4 complex phosphorylated 1 (human)
PR:P24385 hCCND1 PR:000026741 cyclin D1:Cdk4 (human)

Functional Annotation
PRO Term GO Annotation Evidence
Thr-286, MOD:00047
enables GO:0005515 protein binding increased relative to PR:000037511 hCCND1/UnPhos:1 with PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human) PMID:17407548
Thr-286, PR:000026291
associated_with_disease_progression DOID:162 cancer PMID:17407548