Protein Ontology Report - hCCND1 PR:P24385 - http://purl.obolibrary.org/obo/PR_P24385

This page represents a class of proteins encompassing all the protein products of the CCND1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:P24385 Show OBO stanza / PAF / GPI
PRO name	G1/S-specific cyclin-D1 (human)
Synonyms	PRO-short-label: EXACT: hCCND1 Gene-based: RELATED: BCL1 | CCND1 | PRAD1 Other: EXACT: B-cell lymphoma 1 protein (human) | BCL-1 (human) | BCL-1 oncogene (human) | PRAD1 oncogene (human)
Definition	A G1/S-specific cyclin-D1 that is encoded in the genome of human. [PRO:DNx]
PRO Category	organism-gene
Parent	PR:000005121 G1/S-specific cyclin-D1
Gene Template	HGNC:1582 CCND1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 3
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-113832, Reactome:R-HSA-68328, UniProtKB:P24385

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCCND1 forms found in complexes
hCCND1 Component Complexes PR:000005121 CCND1 PR:000026740 cyclin D1:Cdk4 PR:000027132 hCCND1/Phos:1 PR:000027150 cyclin D1:Cdk4 complex phosphorylated 1 (human) PR:P24385 hCCND1 PR:000026741 cyclin D1:Cdk4 (human)

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000027132 hCCND1/Phos:1 Thr-286, MOD:00047 enables GO:0005515 protein binding increased relative to PR:000037511 hCCND1/UnPhos:1 with PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human) PMID:17407548 PR:000037511 hCCND1/UnPhos:1 Thr-286, PR:000026291 associated_with_disease_progression DOID:162 cancer PMID:17407548

top