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Protein Ontology Report - hPML/iso:5

PR:P29590-5 - http://purl.obolibrary.org/obo/PR_P29590-5
Ontology Information
PRO ID PR:P29590-5 Show OBO stanza / PAF / GPI
PRO name transcription factor PML isoform 5 (human)
Synonyms
PRO-short-label: EXACT: hPML/iso:5
Definition A transcription factor PML isoform 5 that is encoded in the genome of human. [PMID:15195100]
PRO Category organism-sequence
Parent PR:000026518 transcription factor PML isoform 5
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P29590-5
hPML/iso:5
acts_upstream_of_or_within GO:0050821 protein stabilization PMID:12773567
acts_upstream_of_or_within GO:0032938 negative regulation of translation in response to oxidative stress PMID:16915281
acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:9448006
acts_upstream_of_or_within GO:0006915 apoptotic process PMID:11080164
acts_upstream_of_or_within GO:0006605 protein targeting PMID:11080164
acts_upstream_of_or_within GO:0030308 negative regulation of cell growth PMID:9448006
acts_upstream_of_or_within GO:0031065 positive regulation of histone deacetylation PMID:11259576
acts_upstream_of_or_within GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage PMID:12402044
acts_upstream_of_or_within GO:0006605 protein targeting PMID:15195100
acts_upstream_of_or_within GO:0051726 regulation of cell cycle PMID:12773567
enables GO:0005515 protein binding with PR:P04637 hTP53 PMID:11080164
enables GO:0005515 protein binding with PR:O15379 hHDAC3 PMID:11259576
enables GO:0005515 protein binding with PR:Q00987 hMDM2 PMID:12915590
enables GO:0005515 protein binding with PR:Q05516 hZBTB16 PMID:9294197
enables GO:0005515 protein binding with PR:Q13547 hHDAC1 PMID:11259576
enables GO:0005515 protein binding with PR:O96017 hCHEK2 PMID:12402044
enables GO:0005515 protein binding with PR:Q00987 hMDM2 PMID:12915590
enables GO:0003713 transcription coactivator activity PMID:15626733
enables GO:0003713 transcription coactivator activity PMID:11080164
enables GO:0005515 protein binding with PR:Q92547 hTOPBP1 PMID:12773567
enables GO:0005515 protein binding with PR:P06400 hRB1 PMID:9448006
enables GO:0005515 protein binding with PR:Q92769 hHDAC2 PMID:11259576
enables GO:0005515 protein binding with PR:P62913 hRPL11 PMID:15195100
enables GO:0005515 protein binding with PR:Q05516 hZBTB16 PMID:9294197
located_in GO:0016363 nuclear matrix PMID:11080164
located_in GO:0005737 cytoplasm PMID:16778193
located_in GO:0016605 PML body PMID:9448006
located_in GO:0005730 nucleolus PMID:16778193
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0016363 nuclear matrix PR:P29590-5 hPML/iso:5

PMID:11080164
GO:0016605 PML body PR:P29590-5 hPML/iso:5

PMID:9448006
GO:0005737 cytoplasm PR:P29590-5 hPML/iso:5

PMID:16778193
GO:0005730 nucleolus PR:P29590-5 hPML/iso:5

PMID:16778193

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