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Protein Ontology Report - hAKT1

PR:P31749 -
This page represents a class of proteins encompassing all the protein products of the AKT1 gene in Homo sapiens.
Ontology Information
PRO ID PR:P31749 Show OBO stanza / PAF / GPI
PRO name RAC-alpha serine/threonine-protein kinase (human)
PRO-short-label: EXACT: hAKT1
Gene-based: RELATED: AKT1 | PKB | RAC
Other: EXACT: PKB alpha (human) | RAC-PK-alpha (human) | protein kinase B (human) | protein kinase B alpha (human) | proto-oncogene c-Akt (human)
Definition A RAC-alpha serine/threonine-protein kinase that is encoded in the genome of human. [PRO:WCB, UniProtKB:P31749]
PRO Category organism-gene
Parent PR:000002190 RAC-alpha serine/threonine-protein kinase
Gene Template HGNC:391 AKT1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 6
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Thr-308, MOD:00047|Ser-473, MOD:00046
acts_upstream_of_or_within GO:0051092 positive regulation of NF-kappaB transcription factor activity PMID:12138205
acts_upstream_of_or_within GO:0032869 cellular response to insulin stimulus PMID:8978681
enables GO:0004672 protein kinase activity PMID:8978681
enables GO:0005515 protein binding with PR:P41279-1 hMAP3K8/iso:1 PMID:12138205
enables GO:0005515 protein binding with PR:O14746-1 hTERT/iso:1 PMID:12586360
enables GO:0004674 protein serine/threonine kinase activity PMID:12138205
Thr-72/Thr-308, MOD:00047|Ser-246/Ser-473, MOD:00046
acts_upstream_of_or_within GO:0043066 negative regulation of apoptotic process PMID:16549426