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Protein Ontology Report - hBMPR1A

PR:P36894 - http://purl.obolibrary.org/obo/PR_P36894
This page represents a class of proteins encompassing all the protein products of the BMPR1A gene in human.
Ontology Information
PRO ID PR:P36894 Show OBO stanza / PAF
PRO name bone morphogenetic protein receptor type-1A (human)
Synonyms
PRO-short-label: EXACT: hBMPR1A
Gene-based: RELATED: ACVRLK3 | ALK3 | BMPR1A
Other: EXACT: ALK-3 (human) | BMP type-1A receptor (human) | BMPR-1A (human) | CD292 (human) | SKR5 (human) | activin receptor-like kinase 3 (human) | serine/threonine-protein kinase receptor R5 (human)
Definition A BMP receptor type-1A that is encoded in the genome of human. [PRO:CNA, UniProtKB:P36894]
PRO Category organism-gene
Parent PR:000000035 BMP receptor type-1A
Gene Template HGNC:1076 BMPR1A
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 9
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000000138
hBMPR1A/var:C82Y
Cys-82, CHEBI:46858 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513
PR:000000139
hBMPR1A/var:C124R
Cys-124, CHEBI:29952 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:11536076
PR:000000144
hBMPR1A/var:M470T
Met-470, CHEBI:30013 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12630959
PR:000000141
hBMPR1A/var:A338D
Ala-338, CHEBI:29958 		associated_with_disease_progression DOID:6457 Cowden syndrome PMID:11536076
PR:000000140
hBMPR1A/var:C130R
Cys-130, CHEBI:29952 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12136244
PR:000000143
hBMPR1A/var:R443C
Arg-443, CHEBI:29950 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513, PMID:17344846
PR:000000142
hBMPR1A/var:C376Y
Cys-376, CHEBI:46858 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:11536076
PR:000036422
hBMPR1A/iso:1/Phos:1
capable_of GO:0004674 protein serine/threonine kinase activity PMID:12829744
located_in GO:0009986 cell surface PMID:10712517
part_of GO:0043235 receptor complex PMID:12829744, PMID:15940369
participates_in GO:0006468 protein phosphorylation PMID:12065756
participates_in GO:0030509 BMP signaling pathway PMID:12829744
PR:P36894-1
hBMPR1A/iso:1
located_in GO:0016021 integral component of membrane PMID:8397373
part_of GO:0043235 receptor complex PMID:15940369
PR:000000137
hBMPR1A/var:Y62D
Tyr-62, CHEBI:29958 		associated_with_disease_progression DOID:0050787 juvenile polyposis syndrome PMID:12417513
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0004674 protein serine/threonine kinase activity PR:000036422 hBMPR1A/iso:1/Phos:1

PMID:12829744
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006468 protein phosphorylation PR:000036422 hBMPR1A/iso:1/Phos:1

PMID:12065756
GO:0030509 BMP signaling pathway PR:000036422 hBMPR1A/iso:1/Phos:1

PMID:12829744
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0009986 cell surface PR:000036422 hBMPR1A/iso:1/Phos:1

PMID:10712517
GO:0016021 integral component of membrane PR:P36894-1 hBMPR1A/iso:1

PMID:8397373

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