Protein Ontology Report - hCDKN2B PR:P42772 - http://purl.obolibrary.org/obo/PR_P42772

This page represents a class of proteins encompassing all the protein products of the CDKN2B gene in human.

Ontology Information
PRO ID	PR:P42772 Show OBO stanza / PAF
PRO name	cyclin-dependent kinase 4 inhibitor B (human)
Synonyms	PRO-short-label: EXACT: hCDKN2B Gene-based: RELATED: CDKN2B | MTS2 Other: EXACT: MTS-2 (human) | multiple tumor suppressor 2 (human) | p14-INK4b (human) | p15-INK4b (human) | p15INK4B (human)
Definition	A cyclin-dependent kinase 4 inhibitor B that is encoded in the genome of human. [PRO:CNA, UniProtKB:P42772]
PRO Category	organism-gene
Parent	PR:000000093 cyclin-dependent kinase 4 inhibitor B
Gene Template	HGNC:1788 CDKN2B
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 4 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-182586, UniProtKB:P42772

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000000093 CDKN2B participates_in GO:0051726 regulation of cell cycle PANTHER:PTHR24144:SF138 PR:P42772-1 hCDKN2B/iso:1 capable_of GO:0005515 protein binding PMID:16169070 capable_of GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PMID:8078588 participates_in GO:0008285 negative regulation of cell population proliferation PMID:8078588 participates_in GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity PMID:8078588 participates_in GO:0051726 regulation of cell cycle PMID:8078588 Molecular Function GO Term Protein Forms & Complexes Evidence GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity PR:P42772-1 hCDKN2B/iso:1 PMID:8078588 GO:0005515 protein binding PR:P42772-1 hCDKN2B/iso:1 PMID:16169070 Biological Process GO Term Protein Forms & Complexes Evidence GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity PR:P42772-1 hCDKN2B/iso:1 PMID:8078588 GO:0008285 negative regulation of cell population proliferation PR:P42772-1 hCDKN2B/iso:1 PMID:8078588 GO:0051726 regulation of cell cycle PR:000000093 CDKN2B PANTHER:PTHR24144:SF138 PR:P42772-1 hCDKN2B/iso:1 PMID:8078588

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