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Protein Ontology Report - mCAPZB/iso:2

PR:P47757-2 -
Ontology Information
PRO ID PR:P47757-2 Show OBO stanza / PAF / GPI
PRO name F-actin-capping protein subunit beta isoform 2 (mouse)
PRO-short-label: EXACT: mCAPZB/iso:2
Other: EXACT: CAPZ beta 2 (mouse) | CAPZ beta-2 (mouse) | CAPZB2 (mouse)
Definition An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse. [PMID:10601341, PRO:KRC]
PRO Category organism-sequence
Parent PR:000035826 F-actin-capping protein subunit beta isoform 2
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mCAPZB/iso:2 forms found in complexes
mCAPZB/iso:2 Component Complexes
PR:P47757-2 mCAPZB/iso:2 PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
PR:P47757-2 mCAPZB/iso:2 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
acts_upstream_of_or_within GO:0031115 negative regulation of microtubule polymerization MGI:4397629, PMID:19806181
acts_upstream_of_or_within GO:0030032 lamellipodium assembly MGI:4397629, PMID:19806181
acts_upstream_of_or_within GO:0051016 barbed-end actin filament capping MGI:3758397, PMID:17656356
acts_upstream_of_or_within GO:0055001 muscle cell development MGI:1350695, PMID:10601341
acts_upstream_of_or_within GO:0031175 neuron projection development MGI:4397629, PMID:19806181
enables GO:0051015 actin filament binding MGI:3758397, PMID:17656356
enables GO:0048487 beta-tubulin binding with PR:Q9ERD7 mTUBB3 MGI:4397629, PMID:19806181
enables GO:0005515 protein binding with PR:Q91YR1 mTWF1 MGI:3773286, PMID:11604420
located_in GO:0014704 intercalated disc MGI:1350695, PMID:10601341
located_in GO:0014704 intercalated disc MGI:68935, PMID:7929588
part_of GO:0008290 F-actin capping protein complex MGI:3773286, PMID:11604420
part_of GO:0008290 F-actin capping protein complex with PR:P47754 mCAPZA2 MGI:4397629, PMID:19806181
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0014704 intercalated disc PR:P47757-2 mCAPZB/iso:2

MGI:1350695, PMID:10601341
PR:P47757-2 mCAPZB/iso:2

MGI:68935, PMID:7929588