Protein Ontology Report - hTGFB2 PR:P61812 - http://purl.obolibrary.org/obo/PR_P61812

This page represents a class of proteins encompassing all the protein products of the TGFB2 gene in Homo sapiens.

Ontology Information
PRO ID	PR:P61812 Show OBO stanza / PAF / GPI
PRO name	transforming growth factor beta-2 (human)
Synonyms	PRO-short-label: EXACT: hTGFB2 Gene-based: RELATED: TGFB2 Other: EXACT: G-TSF (human) | cetermin (human) | glioblastoma-derived T-cell suppressor factor (human)
Definition	A TGF-beta 2 that is encoded in the genome of human. [PRO:CNA, UniProtKB:P61812]
PRO Category	organism-gene
Parent	PR:000000183 TGF-beta 2
Gene Template	HGNC:11768 TGFB2
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 5
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:P61812

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:P61812-1 hTGFB2/iso:A enables GO:0046982 protein heterodimerization activity PMID:2119582 PR:P61812-2 hTGFB2/iso:B enables GO:0046982 protein heterodimerization activity PMID:17845732 located_in GO:0045177 apical part of cell PMID:17845732 PR:000036530 hTGFB2/iso:A/Clv:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:3162913 acts_upstream_of_or_within GO:0008285 negative regulation of cell population proliferation PMID:15944186 enables GO:0001540 amyloid-beta binding PMID:16227582 enables GO:0042803 protein homodimerization activity PMID:2119582, PMID:3476488 enables GO:0005160 transforming growth factor beta receptor binding PMID:16227582 located_in GO:0005615 extracellular space PMID:3162913 PR:000036533 hTGFB2/iso:A/Clv:3 enables GO:0042803 protein homodimerization activity PMID:3476488 located_in GO:0005615 extracellular space PMID:3162913 PR:000036532 hTGFB2/iso:A/Clv:2 part_of GO:0032991 protein-containing complex PMID:3162913 PR:000036535 hTGFB2/iso:B/Clv:2 located_in GO:0005615 extracellular space PMID:1777240 PR:000036534 hTGFB2/iso:B/Clv:1 located_in GO:0005615 extracellular space PMID:1777240 PR:000000183 TGFB2 acts_upstream_of_or_within GO:0008283 cell population proliferation PANTHER:PTHR11848:SF33 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0045177 apical part of cell PR:P61812-2 hTGFB2/iso:B PMID:17845732 GO:0005615 extracellular space PR:000036530 hTGFB2/iso:A/Clv:1 PMID:3162913 PR:000036533 hTGFB2/iso:A/Clv:3 PMID:3162913 PR:000036534 hTGFB2/iso:B/Clv:1 PMID:1777240 PR:000036535 hTGFB2/iso:B/Clv:2 PMID:1777240

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