Protein Ontology Report - hRBX1 PR:P62877 - http://purl.obolibrary.org/obo/PR_P62877

This page represents a class of proteins encompassing all the protein products of the RBX1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:P62877 Show OBO stanza / PAF / GPI
PRO name	E3 ubiquitin-protein ligase RBX1 (human)
Synonyms	PRO-short-label: EXACT: hRBX1 Gene-based: RELATED: RBX1 | RNF75 | ROC1 Other: EXACT: E3 ubiquitin-protein transferase RBX1 (human) | RING finger protein 75 (human) | RING-box protein 1 (human) | Rbx1 (human) | protein ZYP (human) | regulator of cullins 1 (human)
Definition	An E3 ubiquitin-protein ligase RBX1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:P62877]
PRO Category	organism-gene
Parent	PR:000000043 E3 ubiquitin-protein ligase RBX1
Gene Template	HGNC:9928 RBX1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 1
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:P62877

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hRBX1 forms found in complexes
hRBX1 Component Complexes PR:000026756 hRBX1/InitMet- PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human) PR:000026756 hRBX1/InitMet- PR:000026771 SCF beta-TrCP complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000000043 RBX1 acts_upstream_of_or_within GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process PIRSF:PIRSF500724 part_of GO:0019005 SCF ubiquitin ligase complex PIRSF:PIRSF500724 PR:P62877-1 hRBX1/iso:1 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10230407 acts_upstream_of_or_within GO:0006606 protein import into nucleus PMID:11027288 acts_upstream_of_or_within GO:0045116 protein neddylation PMID:15966899 enables GO:0005515 protein binding with PR:Q13616-1 hCUL1/iso:1 PMID:11961546 enables GO:0005515 protein binding with PR:Q9EQW6 mOLIG2 PMID:11027288 part_of GO:0019005 SCF ubiquitin ligase complex PMID:15966899 part_of GO:0000151 ubiquitin ligase complex PMID:16325183 part_of GO:0031462 Cul2-RING ubiquitin ligase complex PMID:15966899 part_of GO:0000151 ubiquitin ligase complex PMID:17217622

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