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Protein Ontology Report - mTHRA

PR:P63058 - http://purl.obolibrary.org/obo/PR_P63058
This page represents a class of proteins encompassing all the protein products of the Thra gene in Mus musculus.
Ontology Information
PRO ID PR:P63058 Show OBO stanza / PAF / GPI
PRO name thyroid hormone receptor alpha (mouse)
Synonyms
PRO-short-label: EXACT: mTHRA
Gene-based: RELATED: C-erba-alpha | Nr1a1 | Thra
Other: EXACT: c-erbA-1 (mouse) | c-erbA-alpha (mouse) | nuclear receptor subfamily 1 group A member 1 (mouse)
Definition A thyroid hormone receptor alpha that is encoded in the genome of mouse. [OMA:P63058, PRO:DNx]
PRO Category organism-gene
Parent PR:000003428 thyroid hormone receptor alpha
Gene Template MGI:98742 Thra
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 4
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:P63058-4
mTHRA/iso:Alpha-deltaE6
acts_upstream_of_or_within GO:0010831 positive regulation of myotube differentiation MGI:3619869, PMID:16322094
acts_upstream_of_or_within GO:0042994 cytoplasmic sequestering of transcription factor MGI:3619869, PMID:16322094
located_in GO:0005737 cytoplasm MGI:3619869, PMID:16322094
PR:P63058
mTHRA
acts_upstream_of_or_within GO:0007611 learning or memory PMID:17129617
acts_upstream_of_or_within GO:0008016 regulation of heart contraction PMID:15240882
acts_upstream_of_or_within GO:0008016 regulation of heart contraction PMID:9430637
acts_upstream_of_or_within GO:0001502 cartilage condensation PMID:9250685
acts_upstream_of_or_within GO:0009887 animal organ morphogenesis PMID:9927422
acts_upstream_of_or_within GO:0001503 ossification PMID:9250685
acts_upstream_of_or_within GO:0001503 ossification PMID:9927422
PR:P63058-1
mTHRA/iso:Alpha-2
acts_upstream_of_or_within GO:0045892 negative regulation of DNA-templated transcription PMID:11641275, PMID:15062575
enables GO:0005515 protein binding with PR:Q924W6 mTRIM66 PMID:15322135
enables GO:0005515 protein binding with PR:Q61645 mHR PMID:11641275
PR:P63058-2
mTHRA/iso:Alpha-1
enables GO:0003727 single-stranded RNA binding MGI:3050934, PMID:15180993
enables GO:0002153 steroid receptor RNA activator RNA binding MGI:3050934, PMID:15180993
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:P63058-4 mTHRA/iso:Alpha-deltaE6

MGI:3619869, PMID:16322094

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