Protein Ontology Report - mSMAD4 PR:P97471 - http://purl.obolibrary.org/obo/PR_P97471

This page represents a class of proteins encompassing all the protein products of the Smad4 gene in Mus musculus.

Ontology Information
PRO ID	PR:P97471 Show OBO stanza / PAF / GPI
PRO name	mothers against decapentaplegic homolog 4 (mouse)
Synonyms	PRO-short-label: EXACT: mSMAD4 Gene-based: RELATED: Dpc4 | Madh4 | Smad4 Other: EXACT: MAD homolog 4 (mouse) | SMAD 4 (mouse) | SMAD family member 4 (mouse) | deletion target in pancreatic carcinoma 4 homolog (mouse) | mothers against DPP homolog 4 (mouse)
Definition	A smad4 that is encoded in the genome of mouse. [OMA:P97471, PRO:DNx]
PRO Category	organism-gene
Parent	PR:000000128 smad4
Gene Template	MGI:894293 Smad4
Taxon	NCBITaxon:10090 Mus musculus
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:P97471

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSMAD4 forms found in complexes
mSMAD4 Component Complexes PR:P97471-1 mSMAD4/iso:1 PR:000025944 smad2-smad4 protein complex 1 (mouse) PR:P97471-1 mSMAD4/iso:1 PR:000025945 smad2-smad4 protein complex 2 (mouse)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000025944 smad2-smad4 protein complex 1 (mouse) acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12672795 located_in GO:0005634 nucleus PMID:12672795 PR:P97471-1 mSMAD4/iso:1 acts_upstream_of_or_within GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17142805 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:16522160 enables GO:0003700 DNA-binding transcription factor activity PMID:12943993, PMID:14633973, PMID:16522160, PMID:16556916 located_in GO:0005634 nucleus PMID:12543979, PMID:12943993, PMID:16522160 part_of GO:0005667 transcription factor complex PMID:14633973, PMID:9288972, PMID:9702197 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:000025944 smad2-smad4 protein complex 1 (mouse) PMID:12672795 PR:P97471-1 mSMAD4/iso:1 PMID:12543979, PMID:12943993, PMID:16522160

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