back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - mFMN1/iso:5

PR:Q05860-5 - http://purl.obolibrary.org/obo/PR_Q05860-5
Ontology Information
PRO ID PR:Q05860-5 Show OBO stanza / PAF / GPI
PRO name formin-1 isoform 5 (mouse)
Synonyms
PRO-short-label: EXACT: mFMN1/iso:5
Other: EXACT: formin-1 (IV) | formin-1 IV (mouse)
Definition A formin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05860-5. [PMID:14647292, PMID:8516300, PRO:KRC]
Comment Note: In PMID:8516300, the amino acid sequences of five formin isoforms were predicted from cDNA sequences and each was produced by in vitro transcription and translation to characterize the apparent molecular masses by SDS-PAGE. The mRNA for isoform IV was also detected in NIH 3T3 cells and primary fibroblast cells and can also be immunoprecipitated from these cells. In PMID:14647292, using the yeast two-hybrid system with alpha-catenin as the bait isolated two independent formin1 clones, one corresponding to formin-1 (IV) and the other a novel transcript called formin-1 (V).
PRO Category organism-sequence
Parent PR:Q05860 formin-1 (mouse)
Taxon NCBITaxon:10090 Mus musculus
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q05860-5
mFMN1/iso:5
acts_upstream_of_or_within GO:0001822 kidney development MGI:1097517, PMID:9234242
enables GO:0005515 protein binding with PR:P26231 mCTNNA1 MGI:3027450, PMID:14647292
located_in GO:0015630 microtubule cytoskeleton MGI:3798334, PMID:18560567
located_in GO:0005737 cytoplasm MGI:3798334, PMID:18560567
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0015630 microtubule cytoskeleton PR:Q05860-5 mFMN1/iso:5

MGI:3798334, PMID:18560567
GO:0005737 cytoplasm PR:Q05860-5 mFMN1/iso:5

MGI:3798334, PMID:18560567

top