Protein Ontology Report - hCDC20 PR:Q12834 - http://purl.obolibrary.org/obo/PR_Q12834

This page represents a class of proteins encompassing all the protein products of the CDC20 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q12834 Show OBO stanza / PAF / GPI
PRO name	cell division cycle protein 20 homolog (human)
Synonyms	PRO-short-label: EXACT: hCDC20 Gene-based: RELATED: CDC20 Other: EXACT: p55CDC (human)
Definition	A cell division cycle protein 20 homolog that is encoded in the genome of human. [PMID:11030144, PMID:20624902, PRO:KER]
PRO Category	organism-gene
Parent	PR:000005188 cell division cycle protein 20 homolog
Gene Template	HGNC:1723 CDC20
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 5
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-141412, Reactome:R-HSA-174112, UniProtKB:Q12834

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCDC20 forms found in complexes
hCDC20 Component Complexes PR:Q12834 hCDC20 PR:000035511 BUB1B:BUB3:MAD2:CDC20 complex (human) PR:Q12834 hCDC20 PR:000035575 BUB1B:CDC20 complex (human)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035369 hCDC20/PhosRes- acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:15525512 enables GO:0004842 ubiquitin-protein transferase activity PMID:15525512 enables GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512 enables GO:0005515 protein binding with PR:O60566 hBUB1B PMID:15525512 located_in GO:0000776 kinetochore PMID:15525512 PR:Q12834 hCDC20 enables GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:20624902 enables GO:0005515 protein binding with PR:O60566 hBUB1B PMID:11030144, PMID:20624902 PR:000035442 hCDC20/Phos:3 enables GO:0005515 protein binding decreased relative to PR:000035369 hCDC20/PhosRes- with PR:O60566 hBUB1B PMID:22566641 PR:000035371 hCDC20/Phos:1 Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling increased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512 enables GO:0004842 ubiquitin-protein transferase activity decreased relative to PR:000035369 hCDC20/PhosRes- PMID:15525512 enables GO:0005515 protein binding with PR:Q13257 hMAD2L1 PMID:15525512 enables GO:0005515 protein binding with PR:O60566 hBUB1B PMID:15525512 located_in GO:0000776 kinetochore PMID:15525512 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000776 kinetochore PR:000035369 hCDC20/PhosRes- PMID:15525512 PR:000035371 hCDC20/Phos:1 Ser-41/Ser-72/Ser-92/Ser-153/Ser-161, MOD:00046|Thr-157, MOD:00047 PMID:15525512

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