PRO Entry Report - PR:Q13315

This page represents a class of proteins encompassing all the protein products of the ATM gene in human.

Protein Forms Annotations

Ontology Information

PRO ID

PR:Q13315 Show OBO stanza / PAF

PRO name

serine-protein kinase ATM (human)

Synonyms

PRO-short-label:	EXACT:	hATM
Gene-based:	RELATED:	ATM
Other:	EXACT:	A-T mutated (human) \| ataxia telangiectasia mutated (human)

Definition

A serine-protein kinase ATM that is encoded in the genome of human. [PRO:CNA]

Comment

Requested by=PubChem.

PRO Category

organism-gene

Parent

PR:000004427 serine-protein kinase ATM

Gene Template

Taxon

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Term Hierarchy Visualization

DAG

OLS

Related Cross References
DB identifiers	DTO:03100033, Reactome:R-HSA-69484, Reactome:R-HSA-9665169, Reactome:R-HSA-9665171, UniProtKB:Q13315

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	capable_of	GO:0004672 protein kinase activity increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307
	located_in	GO:0051233 spindle midzone	PMID:22099307
	located_in	GO:0000779 condensed chromosome, centromeric region	PMID:22099307
	located_in	GO:0000922 spindle pole	PMID:22099307
	located_in	GO:0005694 chromosome	PMID:22099307
	located_in	GO:0030496 midbody	PMID:22099307
	participates_in	GO:0031577 spindle checkpoint signaling increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307
PR:Q13315 hATM	capable_of	GO:0004672 protein kinase activity	PMID:22071147

Molecular Function GO Term	Protein Forms & Complexes	Evidence
GO:0004672 protein kinase activity	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046 increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307
GO:0004672 protein kinase activity	PR:Q13315 hATM	PMID:22071147

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0031577 spindle checkpoint signaling	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046 increased relative to PR:000035452 hATM/PhosRes-	PMID:22099307

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0000779 condensed chromosome, centromeric region	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0030496 midbody	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0000922 spindle pole	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0051233 spindle midzone	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307
GO:0005694 chromosome	PR:000035423 hATM/Phos:2 Ser-1403/Ser-1981, MOD:00046	PMID:22099307

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