Protein Ontology Report - hROCK1 PR:Q13464 - http://purl.obolibrary.org/obo/PR_Q13464

This page represents a class of proteins encompassing all the protein products of the ROCK1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q13464 Show OBO stanza / PAF / GPI
PRO name	Rho-associated protein kinase 1 (human)
Synonyms	PRO-short-label: EXACT: hROCK1 Gene-based: RELATED: ROCK1 Other: EXACT: ROCK-I (human) | Rho-associated, coiled-coil-containing protein kinase 1 (human) | Rho-associated, coiled-coil-containing protein kinase I (human) | p160 ROCK-1 (human) | p160ROCK (human) | renal carcinoma antigen NY-REN-35 (human)
Definition	A Rho-associated protein kinase 1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q13464]
PRO Category	organism-gene
Parent	PR:000000120 Rho-associated protein kinase 1
Gene Template	HGNC:10251 ROCK1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 2
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	DTO:03100456, UniProtKB:Q13464

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000044586 hROCK1/iso:1/UnMod enables GO:0004674 protein serine/threonine kinase activity PMID:11283607 enables GO:0004674 protein serine/threonine kinase activity PMID:15699075 PR:Q13464-1 hROCK1/iso:1 acts_upstream_of_or_within GO:0007266 Rho protein signal transduction PMID:8798490 acts_upstream_of_or_within GO:0030036 actin cytoskeleton organization PMID:10436159 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:10436159 acts_upstream_of_or_within GO:0051260 protein homooligomerization PMID:15291762 enables GO:0031267 small GTPase binding PMID:14660612, PMID:15475352 enables GO:0004674 protein serine/threonine kinase activity PMID:8798490 PR:000026340 hROCK1/iso:1/Clv:1 acts_upstream_of_or_within GO:0006468 protein phosphorylation PMID:11283607 enables GO:0004674 protein serine/threonine kinase activity increased relative to PR:000002529 ROCK1/iso:1/UnMod PMID:11283607

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