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Protein Ontology Report - hROCK1

PR:Q13464 - http://purl.obolibrary.org/obo/PR_Q13464
This page represents a class of proteins encompassing all the protein products of the ROCK1 gene in human.
Ontology Information
PRO ID PR:Q13464 Show OBO stanza / PAF
PRO name Rho-associated protein kinase 1 (human)
Synonyms
PRO-short-label: EXACT: hROCK1
Gene-based: RELATED: ROCK1
Other: EXACT: ROCK-I (human) | Rho-associated, coiled-coil-containing protein kinase 1 (human) | Rho-associated, coiled-coil-containing protein kinase I (human) | p160 ROCK-1 (human) | p160ROCK (human) | renal carcinoma antigen NY-REN-35 (human)
Definition A Rho-associated protein kinase 1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q13464]
PRO Category organism-gene
Parent PR:000000120 Rho-associated protein kinase 1
Gene Template HGNC:10251 ROCK1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 1
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000044586
hROCK1/iso:1/UnMod
capable_of GO:0004674 protein serine/threonine kinase activity PMID:15699075
capable_of GO:0004674 protein serine/threonine kinase activity PMID:11283607
PR:Q13464-1
hROCK1/iso:1
capable_of GO:0031267 small GTPase binding PMID:14660612, PMID:15475352
capable_of GO:0004674 protein serine/threonine kinase activity PMID:8798490
participates_in GO:0051260 protein homooligomerization PMID:15291762
participates_in GO:0006468 protein phosphorylation PMID:10436159
participates_in GO:0007266 Rho protein signal transduction PMID:8798490
participates_in GO:0030036 actin cytoskeleton organization PMID:10436159
PR:000026340
hROCK1/iso:1/Clv:1
capable_of GO:0004674 protein serine/threonine kinase activity increased relative to PR:000002529 ROCK1/iso:1/UnMod PMID:11283607
participates_in GO:0006468 protein phosphorylation PMID:11283607
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0004674 protein serine/threonine kinase activity PR:000026340 hROCK1/iso:1/Clv:1

increased relative to PR:000002529 ROCK1/iso:1/UnMod
PMID:11283607
PR:000044586 hROCK1/iso:1/UnMod

PMID:15699075
PR:000044586 hROCK1/iso:1/UnMod

PMID:11283607
PR:Q13464-1 hROCK1/iso:1

PMID:8798490
GO:0031267 small GTPase binding PR:Q13464-1 hROCK1/iso:1

PMID:14660612, PMID:15475352
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0006468 protein phosphorylation PR:000026340 hROCK1/iso:1/Clv:1

PMID:11283607
PR:Q13464-1 hROCK1/iso:1

PMID:10436159
GO:0007266 Rho protein signal transduction PR:Q13464-1 hROCK1/iso:1

PMID:8798490
GO:0030036 actin cytoskeleton organization PR:Q13464-1 hROCK1/iso:1

PMID:10436159
GO:0051260 protein homooligomerization PR:Q13464-1 hROCK1/iso:1

PMID:15291762

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