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Protein Ontology Report - hSMAD4/iso:1

PR:Q13485-1 - http://purl.obolibrary.org/obo/PR_Q13485-1
Ontology Information
PRO ID PR:Q13485-1 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 4 isoform 1 (human)
Synonyms
PRO-short-label: hSMAD4/iso:1
Definition A smad4 isoform 1 that is encoded in the genome of human. [PRO:CNA]
PRO Category organism-sequence
Parent PR:000000366 smad4 isoform 1
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hSMAD4/iso:1 forms found in complexes
hSMAD4/iso:1 Component Complexes
PR:Q13485-1 hSMAD4/iso:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)
PR:Q13485-1 hSMAD4/iso:1 PR:000025951 smad2-smad4-ski protein complex 1 (human)
PR:Q13485-1 hSMAD4/iso:1 PR:000025947 smad2-smad4 protein complex 4 (human)
PR:Q13485-1 hSMAD4/iso:1 PR:000025946 smad2-smad4 protein complex 3 (human)
PR:Q13485-1 hSMAD4/iso:1 PR:000025940 smad2-smad4 protein complex 2 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q13485-1
hSMAD4/iso:1
capable_of GO:0003700 DNA-binding transcription factor activity PMID:10823886
capable_of GO:0003712 transcription coregulator activity PMID:10980615
located_in GO:0005737 cytoplasm PMID:15280432
located_in GO:0005634 nucleus PMID:10980615, PMID:15280432
part_of GO:0005667 transcription factor complex PMID:12374795
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:17142805, PMID:8774881
participates_in GO:0030509 BMP signaling pathway PMID:14633973
participates_in GO:0007183 SMAD protein complex assembly PMID:10980615, PMID:15350224, PMID:9346966
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030509 BMP signaling pathway PR:Q13485-1 hSMAD4/iso:1

PMID:14633973
GO:0007183 SMAD protein complex assembly PR:Q13485-1 hSMAD4/iso:1

PMID:10980615, PMID:15350224, PMID:9346966
GO:0007179 transforming growth factor beta receptor signaling pathway PR:Q13485-1 hSMAD4/iso:1

PMID:17142805, PMID:8774881
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:Q13485-1 hSMAD4/iso:1

PMID:10980615, PMID:15280432
GO:0005737 cytoplasm PR:Q13485-1 hSMAD4/iso:1

PMID:15280432

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