Protein Ontology Report - hSMAD1 PR:Q15797 - http://purl.obolibrary.org/obo/PR_Q15797

This page represents a class of proteins encompassing all the protein products of the SMAD1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q15797 Show OBO stanza / PAF / GPI
PRO name	mothers against decapentaplegic homolog 1 (human)
Synonyms	PRO-short-label: EXACT: hSMAD1 Gene-based: RELATED: BSP1 | MADH1 | MADR1 | SMAD1 Other: EXACT: BSP-1 (human) | JV4-1 (human) | MAD homolog 1 (human) | Mad-related protein 1 (human) | SMAD 1 (human) | SMAD family member 1 (human) | Smad1 (human) | mothers against DPP homolog 1 (human) | transforming growth factor-beta-signaling protein 1 (human)
Definition	A smad1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q15797]
PRO Category	organism-gene
Parent	PR:000000363 smad1
Gene Template	HGNC:6767 SMAD1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-201468, UniProtKB:Q15797

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000026334 hSMAD1/iso:1/Phos:1 Ser-463/Ser-465, MOD:00046 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785 acts_upstream_of_or_within GO:0007165 signal transduction PMID:9759503 enables GO:0046332 SMAD binding with PR:Q13485 hSMAD4 PMID:9136927 located_in GO:0005634 nucleus PMID:11509558, PMID:9759503 PR:Q15797-1 hSMAD1/iso:1 acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785 acts_upstream_of_or_within GO:0007165 signal transduction PMID:8637600 enables GO:0005515 protein binding with PR:Q7Z3T8 hZFYVE16 PMID:17356069 enables GO:0005102 signaling receptor binding PMID:9136927, PMID:9748228 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949 located_in GO:0005737 cytoplasm PMID:11509558 PR:000036553 hSMAD1/iso:1/PhosUbiq:1 Ser-463/Ser-465, MOD:00046|MOD:01148 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:12857866 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:000026334 hSMAD1/iso:1/Phos:1 Ser-463/Ser-465, MOD:00046 PMID:11509558, PMID:9759503 GO:0005737 cytoplasm PR:Q15797-1 hSMAD1/iso:1 PMID:11509558

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