back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 PRO tracker
 PRO Consortium

Protein Ontology Report - hSMAD1

PR:Q15797 -
This page represents a class of proteins encompassing all the protein products of the SMAD1 gene in human.
Ontology Information
PRO ID PR:Q15797 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 1 (human)
PRO-short-label: EXACT: hSMAD1
Gene-based: RELATED: BSP1 | MADH1 | MADR1 | SMAD1
Other: EXACT: BSP-1 (human) | JV4-1 (human) | MAD homolog 1 (human) | Mad-related protein 1 (human) | SMAD 1 (human) | SMAD family member 1 (human) | Smad1 (human) | mothers against DPP homolog 1 (human) | transforming growth factor-beta-signaling protein 1 (human)
Definition A smad1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q15797]
PRO Category organism-gene
Parent PR:000000363 smad1
Gene Template HGNC:6767 SMAD1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
Ser-463/Ser-465, MOD:00046
acts_upstream_of_or_within GO:0007165 signal transduction PMID:9759503
acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785
enables GO:0046332 SMAD binding with PR:Q13485 hSMAD4 PMID:9136927
located_in GO:0005634 nucleus PMID:11509558, PMID:9759503
acts_upstream_of_or_within GO:0007165 signal transduction PMID:8637600
acts_upstream_of_or_within GO:0030509 BMP signaling pathway PMID:8653785
enables GO:0005102 signaling receptor binding PMID:9136927, PMID:9748228
enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:10708949
enables GO:0005515 protein binding with PR:Q7Z3T8 hZFYVE16 PMID:17356069
located_in GO:0005737 cytoplasm PMID:11509558
Ser-463/Ser-465, MOD:00046|MOD:01148
acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:12857866
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000026334 hSMAD1/iso:1/Phos:1
Ser-463/Ser-465, MOD:00046
PMID:11509558, PMID:9759503
GO:0005737 cytoplasm PR:Q15797-1 hSMAD1/iso:1