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Protein Ontology Report - mSMAD2

PR:Q62432 - http://purl.obolibrary.org/obo/PR_Q62432
This page represents a class of proteins encompassing all the protein products of the Smad2 gene in mouse.
Ontology Information
PRO ID PR:Q62432 Show OBO stanza / PAF
PRO name mothers against decapentaplegic homolog 2 (mouse)
Synonyms
PRO-short-label: EXACT: mSMAD2
Gene-based: RELATED: Madh2 | Madr2 | Smad2
Other: EXACT: MAD homolog 2 (mouse) | Mad-related protein 2 (mouse) | SMAD 2 (mouse) | SMAD family member 2 (mouse) | mMad2 | mothers against DPP homolog 2 (mouse)
Definition A smad2 that is encoded in the genome of mouse. [OMA:Q62432, PRO:DNx]
PRO Category organism-gene
Parent PR:000000364 smad2
Gene Template MGI:108051 Smad2
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 4
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mSMAD2 forms found in complexes
mSMAD2 Component Complexes
PR:000025942 mSMAD2/iso:Long/Phos:1 PR:000025944 smad2-smad4 protein complex 1 (mouse)
PR:000025943 mSMAD2/iso:Short/Phos:1 PR:000025945 smad2-smad4 protein complex 2 (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000025944
smad2-smad4 protein complex 1 (mouse)
located_in GO:0005634 nucleus PMID:12672795
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:12672795
PR:000036555
mSMAD2/iso:Long/PhosUbiq:1
Ser-465/Ser-467, MOD:00046|MOD:01148
capable_of NOT GO:0003713 transcription coactivator activity PMID:15496141
participates_in GO:0007165 signal transduction PMID:15496141
PR:Q62432-1
mSMAD2/iso:Long
located_in GO:0005737 cytoplasm PMID:14701940
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11557747
PR:000025942
mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
capable_of GO:0003713 transcription coactivator activity PMID:15282343
capable_of GO:0046332 SMAD binding with PR:P97471 mSMAD4 PMID:11043574
located_in GO:0005634 nucleus PMID:11557747
participates_in GO:0007165 signal transduction PMID:11262418
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:11262418
PR:000025943
mSMAD2/iso:Short/Phos:1
Ser-435/Ser-437, MOD:00046
capable_of GO:0003700 DNA-binding transcription factor activity PMID:15630024
participates_in GO:0007179 transforming growth factor beta receptor signaling pathway PMID:15630024
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0007179 transforming growth factor beta receptor signaling pathway PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11262418
PR:000025943 mSMAD2/iso:Short/Phos:1
Ser-435/Ser-437, MOD:00046
PMID:15630024
PR:000025944 smad2-smad4 protein complex 1 (mouse)

PMID:12672795
PR:Q62432-1 mSMAD2/iso:Long

PMID:11557747
GO:0007165 signal transduction PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11262418
PR:000036555 mSMAD2/iso:Long/PhosUbiq:1
Ser-465/Ser-467, MOD:00046|MOD:01148
PMID:15496141
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005634 nucleus PR:000025942 mSMAD2/iso:Long/Phos:1
Ser-465/Ser-467, MOD:00046
PMID:11557747
PR:000025944 smad2-smad4 protein complex 1 (mouse)

PMID:12672795
GO:0005737 cytoplasm PR:Q62432-1 mSMAD2/iso:Long

PMID:14701940

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