Protein Ontology Report - frog-BUB1B PR:Q8JGT8 - http://purl.obolibrary.org/obo/PR_Q8JGT8

This page represents a class of proteins encompassing all the protein products of the bub1b gene in Xenopus laevis.

Ontology Information
PRO ID	PR:Q8JGT8 Show OBO stanza / PAF / GPI
PRO name	mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog)
Synonyms	PRO-short-label: EXACT: frog-BUB1B Other: EXACT: xBUBR1
Definition	A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of frog. [PMID:12163471, PMID:15241477, PMID:16950116, PRO:KER]
PRO Category	organism-gene
Parent	PR:000004855 mitotic checkpoint serine/threonine-protein kinase BUB1 beta
Gene Template	NCBIGene:378923 bub1b
Taxon	NCBITaxon:8355 Xenopus laevis
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 0 organism-modification 4
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	UniProtKB:Q8JGT8

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

frog-BUB1B forms found in complexes
frog-BUB1B Component Complexes PR:Q8JGT8 frog-BUB1B PR:000035512 BUB1B:BUB3:MAD2:CDC20 complex (frog) PR:Q8JGT8 frog-BUB1B PR:000035398 BUB1B:APC:EB1 complex (frog)

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000035426 frog-BUB1B/Phos:1 Thr-605, MOD:00047 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:17998400 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17998400 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17998400 enables GO:0005515 protein binding increased relative to PR:000035425 frog-BUB1B/PhosRes- with PR:P70032 frog-plk1 PMID:17998400 PR:000035430 frog-BUB1B/Phos:2 Thr-605, MOD:00047|MOD:00696 enables GO:0004672 protein kinase activity increased relative to PR:000035425 frog-BUB1B/PhosRes- PMID:17998400 PR:000035398 BUB1B:APC:EB1 complex (frog) acts_upstream_of_or_within GO:0051310 metaphase plate congression PMID:17709426 PR:Q8JGT8 frog-BUB1B acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:17709426 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 acts_upstream_of_or_within GO:0034501 protein localization to kinetochore PMID:12163471 acts_upstream_of_or_within GO:0031577 spindle checkpoint signaling PMID:12163471 acts_upstream_of_or_within GO:0051310 metaphase plate congression PMID:17709426 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:12163471 acts_upstream_of_or_within GO:0032092 positive regulation of protein binding PMID:12163471 enables GO:0005515 protein binding with PR:P79935 frog-MAD2L1 PMID:12163471 enables GO:0005515 protein binding with PR:Q6DFD4 frog-CDC20 PMID:12163471 enables GO:0005515 protein binding with PR:Q9YGY3 frog-BUB3 PMID:12163471 enables GO:0004672 protein kinase activity PMID:12163471 enables GO:0005515 protein binding with PR:O42263 frog-CENPE PMID:17709426 enables GO:0005515 protein binding with PR:P70039 frog-APC PMID:17709426 located_in GO:0005694 chromosome PMID:15241477, PMID:16950116 located_in GO:0000776 kinetochore PMID:12163471, PMID:17709426 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0000776 kinetochore PR:Q8JGT8 frog-BUB1B PMID:12163471, PMID:17709426 GO:0005694 chromosome PR:Q8JGT8 frog-BUB1B PMID:15241477, PMID:16950116

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