Protein Ontology Report - hCREBBP PR:Q92793 - http://purl.obolibrary.org/obo/PR_Q92793

This page represents a class of proteins encompassing all the protein products of the CREBBP gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q92793 Show OBO stanza / PAF / GPI
PRO name	CREB-binding protein (human)
Synonyms	PRO-short-label: EXACT: hCREBBP Gene-based: RELATED: CBP | CREBBP Other: EXACT: histone lysine acetyltransferase CREBBP (human) | protein-lysine acetyltransferase CREBBP (human)
Definition	A CREB-binding protein that is encoded in the genome of human. [PMID:11331617]
PRO Category	organism-gene
Parent	PR:000000090 CREB-binding protein
Gene Template	HGNC:2348 CREBBP
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 3 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-193545, UniProtKB:Q92793

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q92793-1 hCREBBP/iso:1 acts_upstream_of_or_within GO:0016573 histone acetylation PMID:11742995 acts_upstream_of_or_within GO:0045893 positive regulation of DNA-templated transcription PMID:11742995 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12169688, PMID:7913207 enables GO:0016407 acetyltransferase activity PMID:11742995 enables GO:0003713 transcription coactivator activity PMID:10733899, PMID:10893273, PMID:12169688, PMID:12586840, PMID:8684459 enables GO:0005515 protein binding with PR:Q92793 hCREBBP PMID:8684459 enables GO:0004402 histone acetyltransferase activity PMID:11742995 enables GO:0005515 protein binding with PR:Q9UER7 hDAXX PMID:11799127 enables GO:0005515 protein binding with PR:P42858 hHTT PMID:10823891 enables GO:0005515 protein binding with PR:P04637 hTP53 PMID:9194564 enables GO:0005515 protein binding with PR:Q16665 hHIF1A PMID:9887100 enables GO:0005515 protein binding with PR:Q14686 hNCOA6 PMID:10866662 enables GO:0005515 protein binding with PR:P55209 hNAP1L1 PMID:11940655 enables GO:0005515 protein binding with PR:Q04206 hRELA PMID:16291753 enables GO:0005515 protein binding with PR:Q99967-1 hCITED2/iso:1 PMID:99104162 enables GO:0005515 protein binding with PR:P17096 hHMGA1 PMID:10428834 located_in GO:0005634 nucleus PMID:7913207 part_of GO:0000123 histone acetyltransferase complex PMID:9742083 PR:000000266 hCREBBP/var:R1378P Arg-1378, CHEBI:50342 associated_with_disease_progression DOID:1933 Rubinstein-Taybi syndrome PMID:11331617 enables NOT GO:0004402 histone acetyltransferase activity PMID:11331617 has_agent SO:0001559 polypeptide_loss_of_function_variant PMID:11331617 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005634 nucleus PR:Q92793-1 hCREBBP/iso:1 PMID:7913207

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