Protein Ontology Report - hSMURF1 PR:Q9HCE7 - http://purl.obolibrary.org/obo/PR_Q9HCE7

This page represents a class of proteins encompassing all the protein products of the SMURF1 gene in Homo sapiens.

Ontology Information
PRO ID	PR:Q9HCE7 Show OBO stanza / PAF / GPI
PRO name	E3 ubiquitin-protein ligase SMURF1 (human)
Synonyms	PRO-short-label: EXACT: hSMURF1 Gene-based: RELATED: KIAA1625 | SMURF1 Other: EXACT: HECT-type E3 ubiquitin transferase SMURF1 (human) | SMAD ubiquitination regulatory factor 1 (human) | SMAD-specific E3 ubiquitin-protein ligase 1 (human)
Definition	An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9HCE7]
PRO Category	organism-gene
Parent	PR:000000361 E3 ubiquitin-protein ligase SMURF1
Gene Template	HGNC:16807 SMURF1
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 2 organism-modification 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-3004548, Reactome:R-HSA-975972, UniProtKB:Q9HCE7

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:Q9HCE7 hSMURF1 acts_upstream_of_or_within GO:0030514 negative regulation of BMP signaling pathway PMID:10458166 PR:Q9HCE7-2 hSMURF1/iso:Short acts_upstream_of_or_within GO:0036211 protein modification process PMID:10458166 acts_upstream_of_or_within GO:0006511 ubiquitin-dependent protein catabolic process PMID:10458166 acts_upstream_of_or_within GO:0030579 ubiquitin-dependent SMAD protein catabolic process PMID:12857866 enables GO:0004842 ubiquitin-protein transferase activity PMID:10458166 enables GO:0005515 protein binding PMID:11278251, PMID:16299379 located_in GO:0005622 intracellular anatomical structure PMID:10458166 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0005622 intracellular anatomical structure PR:Q9HCE7-2 hSMURF1/iso:Short PMID:10458166

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