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Protein Ontology Report - hIRAK4

PR:Q9NWZ3 - http://purl.obolibrary.org/obo/PR_Q9NWZ3
This page represents a class of proteins encompassing all the protein products of the IRAK4 gene in human.
Ontology Information
PRO ID PR:Q9NWZ3 Show OBO stanza / PAF
PRO name interleukin-1 receptor-associated kinase 4 (human)
Synonyms
PRO-short-label: EXACT: hIRAK4
Gene-based: RELATED: IRAK4
Other: EXACT: IRAK-4 (human) | renal carcinoma antigen NY-REN-64 (human)
Definition An interleukin-1 receptor-associated kinase 4 that is encoded in the genome of human. [PRO:CNA]
PRO Category organism-gene
Parent PR:000001780 interleukin-1 receptor-associated kinase 4
Gene Template HGNC:17967 IRAK4
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 3
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hIRAK4 forms found in complexes
hIRAK4 Component Complexes
PR:000001780 IRAK4 PR:000027182 IRAK4:MYD88:TIRAP:activated TLR4 complex
PR:000027184 hIRAK4/UnMod PR:000027183 IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
PR:000027191 hIRAK4/iso:1/Phos:1 PR:000027495 pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
PR:000027191 hIRAK4/iso:1/Phos:1 PR:000027192 pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000027183
IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
PR:000027192
pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
PR:000027495
pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894

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