[Term]
id: GO:1990265
name: platelet-derived growth factor complex
namespace: cellular_component
def: "A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD)." [GOC:bhm, PMID:11331882]
comment: An example of this is PDGFA in human (P04085) in PMID:20534510 (inferred from direct assay).
synonym: "PDGF complex" RELATED []
is_a: GO:0032991 ! protein-containing complex