[Term] id: PR:000025419 name: chordin proteolytic cleavage product def: "A chordin that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "CHRD/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000000010 ! chordin [Term] id: PR:Q9Z0E2 name: chordin (mouse) def: "A chordin that is encoded in the genome of mouse." [OMA:Q9Z0E2, PRO:DNx] comment: Category=organism-gene. synonym: "Chrd" RELATED Gene-based [UniProtKB:Q9Z0E2] synonym: "mCHRD" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z0E2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000010 ! chordin relationship: has_gene_template MGI:1313268 ! Chrd (mouse) [Term] id: PR:Q91713-1 name: chordin isoform 1 (frog) def: "A chordin isoform 1 that is encoded in the genome of frog." [PRO:DAN] comment: Category=organism-sequence. synonym: "frog-CHRD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q91713-1 intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000000086 ! chordin isoform 1 [Term] id: PR:000036410 name: chordin isoform 1, signal peptide removed form (frog) def: "A chordin isoform 1, signal peptide removed form in frog. UniProtKB:Q91713-1, 20-941." [PMID:8752213, PRO:CNA] comment: Category=organism-modification. synonym: "PRO_0000005367" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "frog-CHRD/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q91713-1, 20-941" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000000424 ! chordin isoform 1, signal peptide removed form [Term] id: PR:000036411 name: chordin isoform 1 cleaved 2 (mouse) def: "A chordin isoform 1 cleaved 2 in mouse. UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, PRO:CNA] comment: Category=organism-modification. synonym: "mCHRD/iso:1/Clv:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9Z0E2-1, 154-861" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000425 ! chordin isoform 1 cleaved 2 [Term] id: PR:000000086 name: chordin isoform 1 def: "A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-1 or a 1:1 ortholog thereof." [PMID:10479448, PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "CHRD/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000010 ! chordin [Term] id: PR:000000087 name: chordin isoform 2 def: "A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-2 or a 1:1 ortholog thereof." [PMID:11472837, PRO:CNA, PRO:DNx, UniProtKB:Q9H2X0-2] comment: Category=sequence. synonym: "P-CR1" RELATED [] synonym: "CHRD/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000010 ! chordin [Term] id: PR:000000088 name: chordin isoform 4 def: "A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-4 or a 1:1 ortholog thereof." [PMID:11472837, PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "CHRD/iso:4" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000010 ! chordin [Term] id: PR:000000089 name: chordin isoform 5 def: "A chordin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-5 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN] comment: Category=sequence. synonym: "CHRD/iso:5" EXACT PRO-short-label [PRO:DNx] synonym: "CHRD sequence 4 cleaved-1" EXACT [] is_a: PR:000000010 ! chordin [Term] id: PR:Q9Z0E2-1 name: chordin isoform 1 (mouse) def: "A chordin isoform 1 that is encoded in the genome of mouse." [PRO:CNA] comment: Category=organism-sequence. synonym: "mCHRD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9Z0E2-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000086 ! chordin isoform 1 [Term] id: PR:Q9H2X0 name: chordin (human) def: "A chordin that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q9H2X0] comment: Category=organism-gene. synonym: "CHRD" RELATED Gene-based [UniProtKB:Q9H2X0] synonym: "hCHRD" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ217/PRO243" RELATED Gene-based [UniProtKB:Q9H2X0] xref: UniProtKB:Q9H2X0 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000010 ! chordin relationship: has_gene_template HGNC:1949 ! CHRD (human) [Term] id: PR:000000424 name: chordin isoform 1, signal peptide removed form def: "A chordin isoform 1 that has had the signal peptide removed." [PRO:CNA] comment: Category=modification. synonym: "CHRD/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "chordin isoform 1 cleaved 1" EXACT [] intersection_of: PR:000000086 ! chordin isoform 1 intersection_of: lacks_part SO:0000418 ! signal_peptide [Term] id: PR:000000425 name: chordin isoform 1 cleaved 2 def: "A chordin isoform 1 that has been cleaved by BMP1 at two sites upstream of Asp residues. One site is within the motif Y[SN]DR, whereas the other is within the motif MQ[AS]DG. This form activates BMP signaling pathway. Example: UniProtKB:Q9Z0E2-1, 154-861." [PMID:10479448, UniProtKB:Q9Z0E2] comment: Category=modification. synonym: "CHRD/iso:1/Clv:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000086 ! chordin isoform 1 relationship: output_of GO:0016485 ! protein processing [Term] id: PR:Q91713 name: chordin (frog) def: "A chordin that is encoded in the genome of frog." [PRO:DAN] comment: Category=organism-gene. synonym: "chrd" RELATED Gene-based [UniProtKB:Q91713] synonym: "frog-CHRD" EXACT PRO-short-label [PRO:DNx] synonym: "organizer-specific secreted-dorsalizing factor (frog)" EXACT [UniProtKB:Q91713] xref: UniProtKB:Q91713 intersection_of: only_in_taxon NCBITaxon:8355 ! Xenopus laevis intersection_of: PR:000000010 ! chordin relationship: has_gene_template NCBIGene:398045 ! chrd (frog) [Term] id: PR:Q9H2X0-1 name: chordin isoform 1 (human) def: "A chordin isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hCHRD/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H2X0-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000086 ! chordin isoform 1 [Term] id: PR:Q9H2X0-2 name: chordin isoform 2 (human) def: "A chordin isoform 2 that is encoded in the genome of human." [PRO:CNA, PRO:DNx] comment: Category=organism-sequence. synonym: "hCHRD/iso:2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H2X0-2 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000087 ! chordin isoform 2 [Term] id: PR:Q9H2X0-3 name: chordin isoform h3 (human) def: "A chordin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H2X0-3." [PRO:DNx, UniProtKB:Q9H2X0] comment: Category=organism-sequence. synonym: "hCHRD/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H2X0-3 is_a: PR:Q9H2X0 ! chordin (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9H2X0-4 name: chordin isoform 4 (human) def: "A chordin isoform 4 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hCHRD/iso:4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H2X0-4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000088 ! chordin isoform 4 [Term] id: PR:Q9H2X0-5 name: chordin isoform 5 (human) def: "A chordin isoform 5 that is encoded in the genome of human." [PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hCHRD/iso:5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9H2X0-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000089 ! chordin isoform 5 [Term] id: PR:000036409 name: chordin isoform 1, signal peptide removed form (mouse) def: "A chordin isoform 1, signal peptide removed form in mouse. UniProtKB:Q9Z0E2-1, 27-948." [PMID:10479448, PMID:11784076, PMID:15381701, PMID:15780974, PRO:CNA] comment: Category=organism-modification. synonym: "PRO_0000005365" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "mCHRD/iso:1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9Z0E2-1, 27-948" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000000424 ! chordin isoform 1, signal peptide removed form [Term] id: PR:000000010 name: chordin def: "A protein that is a translation product of the human CHRD gene or a 1:1 ortholog thereof. Chordin regulates signaling by BMP pathway." [PRO:CNA] comment: Category=gene. synonym: "CHRD" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ217/PRO243" RELATED Gene-based [] xref: PIRSF:PIRSF002496 is_a: PR:000000001 ! protein [Term] id: PR:Q63148 name: chordin (rat) def: "A chordin that is encoded in the genome of rat." [OMA:Q63148, PANTHER:PTHR11339:SF113, PRO:DNx] comment: Category=organism-gene. synonym: "Chrd" RELATED Gene-based [UniProtKB:Q63148] synonym: "rCHRD" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q63148 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000000010 ! chordin relationship: has_gene_template RGD:620181 ! Chrd (rat) [Term] id: PR:O57472 name: chordin (zebrafish) def: "A chordin that is encoded in the genome of zebrafish." [PRO:CNA] comment: Category=organism-gene. synonym: "chd" RELATED Gene-based [UniProtKB:O57472] synonym: "chrd" RELATED Gene-based [UniProtKB:O57472] synonym: "z-CHRD" EXACT PRO-short-label [PRO:DNx] synonym: "protein chordino (zebrafish)" EXACT [UniProtKB:O57472] xref: UniProtKB:O57472 intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio intersection_of: PR:000000010 ! chordin relationship: has_gene_template ZFIN:ZDB-GENE-990415-33 ! chrd (zebrafish) [Term] id: PR:Q24025 name: dorsal-ventral patterning protein Sog (fruit fly) def: "A chordin that is encoded in the genome of fruit fly." [OMA:Q24025, PRO:DNx] comment: Category=organism-gene. synonym: "sog" RELATED Gene-based [UniProtKB:Q24025] synonym: "CG9224" RELATED Gene-based [UniProtKB:Q24025] synonym: "fly-CHRD" EXACT PRO-short-label [PRO:DNx] synonym: "short gastrulation protein (fruit fly)" EXACT [UniProtKB:Q24025] xref: UniProtKB:Q24025 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000000010 ! chordin relationship: has_gene_template FlyBase:FBgn0003463 ! sog (fruit fly)