[Term] id: PR:Q04771 name: activin receptor type-1 (human) def: "An activin receptor type-1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q04771] comment: Category=organism-gene. Requested by=PubChem. synonym: "ACVR1" RELATED Gene-based [UniProtKB:Q04771] synonym: "hACVR1" EXACT PRO-short-label [PRO:DNx] synonym: "ACVRLK2" RELATED Gene-based [UniProtKB:Q04771] synonym: "SKR1 (human)" EXACT [UniProtKB:Q04771] synonym: "ALK-2 (human)" EXACT [UniProtKB:Q04771] synonym: "TSR-I (human)" BROAD [UniProtKB:Q04771] synonym: "ACTR-I (human)" EXACT [UniProtKB:Q04771] synonym: "activin receptor type I (human)" EXACT [UniProtKB:Q04771] synonym: "activin receptor-like kinase 2 (human)" EXACT [UniProtKB:Q04771] synonym: "TGF-B superfamily receptor type I (human)" BROAD [UniProtKB:Q04771] synonym: "serine/threonine-protein kinase receptor R1 (human)" EXACT [UniProtKB:Q04771] xref: DTO:03100012 xref: UniProtKB:Q04771 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000067 ! activin receptor type-1 relationship: has_gene_template HGNC:171 ! ACVR1 (human) [Term] id: PR:000000200 name: activin receptor type-1 sequence variant R206H (human) def: "An activin receptor type-1 (human) that has a His residue at the position equivalent to Arg-206 of the amino acid sequence represented by UniProtKB:Q04771. This variation is located within the GS-motif. UniProtKB:Q04771, Arg-206, CHEBI:29979." [PMID:8397373, PRO:CNA, PRO:DAN] comment: Category=organism-sequence. synonym: "hACVR1/var:R206H" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q04771, Arg-206, CHEBI:29979" EXACT PRO-proteoform-std [PRO:DAN] synonym: "activin receptor type-1 sequence variant 1 (human)" EXACT [PRO:DNx] xref: UniProtKB_VAR:VAR_028244 is_a: PR:Q04771 ! activin receptor type-1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q04771-1 name: activin receptor type-1 isoform 1 (human) def: "An activin receptor type-1 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hACVR1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q04771-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000199 ! activin receptor type-1 isoform 1 [Term] id: PR:000000067 name: activin receptor type-1 def: "A TGF-beta superfamily receptor type-1 that is a translation product of the human ACVR1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "SKR1" EXACT [] synonym: "ACVR1" EXACT PRO-short-label [PRO:DNx] synonym: "ALK-2" EXACT [] synonym: "TSR-I" RELATED [] synonym: "Tgfb1" RELATED Gene-based [] synonym: "ACTR-I" EXACT [] synonym: "TSK-7L" EXACT [] synonym: "ACVRLK2" RELATED Gene-based [] synonym: "activin receptor type I" EXACT [] synonym: "activin receptor-like kinase 2" EXACT [] synonym: "TGF-B superfamily receptor type I" RELATED [] synonym: "serine/threonine-protein kinase receptor R1" EXACT [] xref: IUPHARobj:1785 is_a: PR:000000006 ! TGF-beta superfamily receptor type-1 [Term] id: PR:000036435 name: activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 (human) def: "An activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 in human." [PMID:8242742, PMID:8389764, PMID:8397373, PRO:CNA] comment: Category=organism-modification. synonym: "hACVR1/iso:1/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000524 ! activin receptor type-1 isoform 1, signal peptide removed phosphorylated 1 relationship: has_part MOD:00696 ! phosphorylated residue