[Term]
id: PR:000021897
name: decorin isoform A, signal peptide removed form
def: "A decorin isoform A that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "DCN/iso:A/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000000271 ! decorin isoform A
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000000094
name: decorin
def: "A class 1 small leucine-rich proteoglycan that is a translation product of the human DCN gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "DCN" EXACT PRO-short-label [PRO:DNx]
synonym: "PG40" EXACT []
synonym: "PG-S2" EXACT []
synonym: "SLRR1B" RELATED Gene-based []
synonym: "bone proteoglycan II" EXACT []
is_a: PR:000000011 ! class 1 small leucine-rich proteoglycan

[Term]
id: PR:P07585
name: decorin (human)
def: "A decorin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P07585]
comment: Category=organism-gene.
synonym: "DCN" RELATED Gene-based [UniProtKB:P07585]
synonym: "hDCN" EXACT PRO-short-label [PRO:DNx]
synonym: "SLRR1B" RELATED Gene-based [UniProtKB:P07585]
synonym: "PG40 (human)" EXACT [UniProtKB:P07585]
synonym: "PG-S2 (human)" EXACT [UniProtKB:P07585]
synonym: "bone proteoglycan II (human)" EXACT [UniProtKB:P07585]
xref: Reactome:R-HSA-2534176 "PR:P07585 located_in GO:0005576"
xref: UniProtKB:P07585
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000094 ! decorin
relationship: has_gene_template HGNC:2705 ! DCN (human)

[Term]
id: PR:P07585-1
name: decorin isoform A (human)
def: "A decorin isoform A that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hDCN/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07585-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000271 ! decorin isoform A

[Term]
id: PR:P07585-3
name: decorin isoform C (human)
def: "A decorin isoform C that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]
comment: Category=organism-sequence.
synonym: "hDCN/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07585-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000273 ! decorin isoform C

[Term]
id: PR:P07585-2
name: decorin isoform B (human)
def: "A decorin isoform B that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]
comment: Category=organism-sequence.
synonym: "hDCN/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07585-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000272 ! decorin isoform B

[Term]
id: PR:P07585-5
name: decorin isoform E (human)
def: "A decorin isoform E that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]
comment: Category=organism-sequence.
synonym: "hDCN/iso:E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07585-5
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000275 ! decorin isoform E

[Term]
id: PR:P07585-4
name: decorin isoform D (human)
def: "A decorin isoform D that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07585]
comment: Category=organism-sequence.
synonym: "hDCN/iso:D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07585-4
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000274 ! decorin isoform D

[Term]
id: PR:000000273
name: decorin isoform C
def: "A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-3 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: The indicated mRNA lacks exons 3, 4 and 5 in the coding region compared to isoform 1. This causes an internal frameshift and the encoded isoform is shorter. Thus it is not clear if cleavage takes place for the mature peptide to be produced from the proprotein.
synonym: "DCN/iso:C" EXACT PRO-short-label [PRO:DNx]
synonym: "DCN isoform 3" EXACT [PRO:DNx]
is_a: PR:000000094 ! decorin

[Term]
id: PR:000000272
name: decorin isoform B
def: "A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-2 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: The encoded protein lacks a strech of approximately 100 amino acids after the propeptide region. Thus it is not clear if cleavage takes place for the mature peptide to be produced from the proprotein.
synonym: "DCN/iso:B" EXACT PRO-short-label [PRO:DNx]
synonym: "DCN isoform 2" EXACT [PRO:DNx]
is_a: PR:000000094 ! decorin

[Term]
id: PR:000000271
name: decorin isoform A
def: "A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "DCN/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "DCN isoform 1" EXACT [PRO:DNx]
is_a: PR:000000094 ! decorin

[Term]
id: PR:000000275
name: decorin isoform E
def: "A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-5 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: The indicated mRNA lacks exons 3, 4, 5, 6, and 7 in the coding region compared to isoform 1. This causes an internal frameshift and the encoded isoform is shorter. Thus it is not clear if cleavage takes place for the mature peptide to be produced from the proprotein.
synonym: "DCN/iso:E" EXACT PRO-short-label [PRO:DNx]
synonym: "decorin isoform 5" EXACT [PRO:DNx]
is_a: PR:000000094 ! decorin

[Term]
id: PR:000000274
name: decorin isoform D
def: "A decorin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07585-4 or a 1:1 ortholog thereof." [NCBIGene:1634, PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: The indicated mRNA lacks exons 4, 5, 6, and 7 in the coding region compared to isoform 1. The encoded isoform lacks a stretch of approximately 187 amino acids. Thus it is not clear if cleavage takes place for the mature peptide to be produced from the proprotein.
synonym: "DCN/iso:D" EXACT PRO-short-label [PRO:DNx]
synonym: "DCN isoform 4" EXACT [PRO:DNx]
is_a: PR:000000094 ! decorin

[Term]
id: PR:000036456
name: decorin isoform A, mature form (human)
def: "A decorin isoform A, mature form in human. UniProtKB:P07585-1, 31-359." [PMID:17651433, PMID:9988678, PRO:CNA]
comment: Category=organism-modification.
synonym: "PRO_0000032710" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDCN/iso:A/mature" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07585-1, 31-359" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2063995 "PR:000036456 located_in GO:0005796"
xref: Reactome:R-HSA-2065260 "PR:000036456 located_in GO:0043202"
xref: Reactome:R-HSA-1430775 "PR:000036456 located_in GO:0005576"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000544 ! decorin isoform A, mature form

[Term]
id: PR:000036457
name: decorin isoform A cleaved and glycosylated 1 (human)
def: "A decorin isoform A cleaved and glycosylated 1 in human. UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PMID:17651433, PMID:9988678, PRO:CNA, PRO:DAN]
comment: Category=organism-modification.
synonym: "hDCN/iso:A/ClvGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000032710, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000545 ! decorin isoform A cleaved and glycosylated 1
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: has_part MOD:00814 ! O-xylosyl-L-serine

[Term]
id: PR:000000429
name: decorin isoform A cleaved and glycosylated form
def: "A decorin isoform A, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "DCN/iso:A/ClvGlyco+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00693 ! glycosylated residue
intersection_of: PR:000021897 ! decorin isoform A, signal peptide removed form
intersection_of: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:P28675
name: decorin (chicken)
def: "A decorin that is encoded in the genome of chicken." [OMA:P28675, PANTHER:PTHR24369:SF152, PRO:DNx]
comment: Category=organism-gene.
synonym: "DCN" RELATED Gene-based [UniProtKB:P28675]
synonym: "chick-DCN" EXACT PRO-short-label [PRO:DNx]
synonym: "PG-S2 (chicken)" EXACT [UniProtKB:P28675]
synonym: "bone proteoglycan II (chicken)" EXACT [UniProtKB:P28675]
xref: UniProtKB:P28675
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000000094 ! decorin
relationship: has_gene_template NCBIGene:417892 ! DCN (chicken)

[Term]
id: PR:000018276
name: decorin proteolytic cleavage product
def: "A decorin that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "DCN/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000000094 ! decorin

[Term]
id: PR:P28654
name: decorin (mouse)
def: "A decorin that is encoded in the genome of mouse." [OMA:P28654, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dcn" RELATED Gene-based [UniProtKB:P28654]
synonym: "mDCN" EXACT PRO-short-label [PRO:DNx]
synonym: "PG40 (mouse)" EXACT [UniProtKB:P28654]
synonym: "PG-S2 (mouse)" EXACT [UniProtKB:P28654]
synonym: "bone proteoglycan II (mouse)" EXACT [UniProtKB:P28654]
xref: UniProtKB:P28654
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000094 ! decorin
relationship: has_gene_template MGI:94872 ! Dcn (mouse)

[Term]
id: PR:Q01129
name: decorin (rat)
def: "A decorin that is encoded in the genome of rat." [OMA:Q01129, PANTHER:PTHR24369:SF152, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dcn" RELATED Gene-based [UniProtKB:Q01129]
synonym: "rDCN" EXACT PRO-short-label [PRO:DNx]
synonym: "DSPG (rat)" EXACT [UniProtKB:Q01129]
synonym: "PG40 (rat)" EXACT [UniProtKB:Q01129]
synonym: "PG-S2 (rat)" EXACT [UniProtKB:Q01129]
synonym: "bone proteoglycan II (rat)" EXACT [UniProtKB:Q01129]
synonym: "dermatan sulfate proteoglycan-II (rat)" EXACT [UniProtKB:Q01129]
xref: UniProtKB:Q01129
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000094 ! decorin
relationship: has_gene_template RGD:61895 ! Dcn (rat)

[Term]
id: PR:000000545
name: decorin isoform A cleaved and glycosylated 1
def: "A decorin isoform A cleaved and glycosylated form that has been modified with O-linked glycosaminoglycan at the most N-terminal SG site and additional N-linked glycosylated Asn residues. Example: UniProtKB:P07585-1, 31-359, Ser-34, MOD:00814|Asn-211/Asn-262/Asn-303, MOD:00160." [PMID:16258169, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "DCN/iso:A/ClvGlyco:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000429 ! decorin isoform A cleaved and glycosylated form
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: has_part MOD:00814 ! O-xylosyl-L-serine

[Term]
id: PR:000000544
name: decorin isoform A, mature form
def: "A decorin isoform A, signal peptide removed form that has been processed by subsequent removal of the propeptide, rendering the mature decorin protein core." [PRO:CNA]
comment: Category=modification.
synonym: "DCN/iso:A/mature" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000021897 ! decorin isoform A, signal peptide removed form
intersection_of: lacks_part SO:0001062 ! propeptide

[Term]
id: PR:000000550
name: decorin isoform A cleaved 2
def: "A decorin isoform A that has been cleaved after the Phe residue within the F[NS]GLN motif as a result of the catabolic processing of decorin. This form lacks most of the leucine-rich domains and is abundant in adult skin tissue." [PMID:12621051]
comment: Category=modification.
synonym: "decorunt" RELATED []
synonym: "DCN/iso:A/Clv:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000271 ! decorin isoform A
relationship: output_of GO:0016485 ! protein processing

[Term]
id: PR:000036460
name: decorin isoform A cleaved 2 (human)
def: "A decorin isoform A cleaved 2 in human. UniProtKB:P07585-1, ?-170." [PMID:12621051, PRO:CNA]
comment: Category=organism-modification.
synonym: "hDCN/iso:A/Clv:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07585-1, ?-170" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000550 ! decorin isoform A cleaved 2