[Term]
id: PR:P28749-1
name: retinoblastoma-like protein 1 isoform 1 (human)
def: "A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hRBL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28749-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000303 ! retinoblastoma-like protein 1 isoform 1

[Term]
id: PR:P28749-2
name: retinoblastoma-like protein 1 isoform 2 (human)
def: "A retinoblastoma-like protein 1 isoform 2 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hRBL1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28749-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000304 ! retinoblastoma-like protein 1 isoform 2

[Term]
id: PR:P28749
name: retinoblastoma-like protein 1 (human)
def: "A retinoblastoma-like protein 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:P28749]
comment: Category=organism-gene.
synonym: "RBL1" RELATED Gene-based [UniProtKB:P28749]
synonym: "hRBL1" EXACT PRO-short-label [PRO:DNx]
synonym: "p107 (human)" BROAD [UniProtKB:P28749]
synonym: "pRb1 (human)" EXACT [UniProtKB:P28749]
synonym: "107 kDa retinoblastoma-associated protein (human)" EXACT [UniProtKB:P28749]
xref: Reactome:R-HSA-389104 "PR:P28749 located_in GO:0005654"
xref: UniProtKB:P28749
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000118 ! retinoblastoma-like protein 1
relationship: has_gene_template HGNC:9893 ! RBL1 (human)

[Term]
id: PR:000000458
name: retinoblastoma-like protein 1 isoform 1 phosphorylated form
def: "A retinoblastoma-like protein 1 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
comment: Category=modification.
synonym: "RBL1/iso:1/PhosRes+" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part MOD:00696 ! phosphorylated residue
intersection_of: PR:000000303 ! retinoblastoma-like protein 1 isoform 1

[Term]
id: PR:Q64701-2
name: retinoblastoma-like protein 1 isoform Short (mouse)
def: "A retinoblastoma-like protein 1 isoform 3 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mRBL1/iso:Short" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64701-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000305 ! retinoblastoma-like protein 1 isoform 3

[Term]
id: PR:000000118
name: retinoblastoma-like protein 1
def: "A retinoblastoma-like protein that is a translation product of the human RBL1 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "RBL1" EXACT PRO-short-label [PRO:DNx]
synonym: "p107" BROAD [PRO:DNx]
synonym: "pRb1" EXACT []
synonym: "107 kDa retinoblastoma-associated protein" EXACT []
is_a: PR:000000023 ! retinoblastoma-like protein

[Term]
id: PR:000000303
name: retinoblastoma-like protein 1 isoform 1
def: "A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "RBL1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000118 ! retinoblastoma-like protein 1

[Term]
id: PR:000049024
name: retinoblastoma-like protein 1 phosphorylated 1 (human)
def: "A retinoblastoma-like protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Thr-369, and phosphoserine at positions 640, 964 and 975 of the amino acid sequence represented by UniProtKB:P28749. UniProtKB:P28749, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PRO:DNx, Reactome:R-HSA-1226085]
comment: Category=organism-modification.
synonym: "hRBL1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28749, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1226085 "PR:000049024 located_in GO:0005654"
is_a: PR:P28749 ! retinoblastoma-like protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q64701
name: retinoblastoma-like protein 1 (mouse)
def: "A retinoblastoma-like protein 1 that is encoded in the genome of mouse." [OMA:Q64701, PRO:DNx]
comment: Category=organism-gene.
synonym: "Rbl1" RELATED Gene-based [UniProtKB:Q64701]
synonym: "mRBL1" EXACT PRO-short-label [PRO:DNx]
synonym: "p107 (mouse)" BROAD [UniProtKB:Q64701]
synonym: "pRb1 (mouse)" EXACT [UniProtKB:Q64701]
synonym: "107 kDa retinoblastoma-associated protein (mouse)" EXACT [UniProtKB:Q64701]
xref: UniProtKB:Q64701
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000118 ! retinoblastoma-like protein 1
relationship: has_gene_template MGI:103300 ! Rbl1 (mouse)

[Term]
id: PR:D3ZS28
name: retinoblastoma-like protein 1 (rat)
def: "A retinoblastoma-like protein 1 that is encoded in the genome of rat." [OMA:D3ZS28, PRO:DNx]
comment: Category=organism-gene.
synonym: "Rbl1" RELATED Gene-based [UniProtKB:D3ZS28]
synonym: "rRBL1" EXACT PRO-short-label [PRO:DNx]
synonym: "p107 (rat)" BROAD [UniProtKB:D3ZS28]
synonym: "pRb1 (rat)" EXACT [UniProtKB:D3ZS28]
synonym: "107 kDa retinoblastoma-associated protein (rat)" EXACT [UniProtKB:D3ZS28]
xref: UniProtKB:D3ZS28
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000000118 ! retinoblastoma-like protein 1
relationship: has_gene_template RGD:1595511 ! Rbl1 (rat)

[Term]
id: PR:000000305
name: retinoblastoma-like protein 1 isoform 3
def: "A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q64701-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence. Note: This isoform lacks the C-terminal retinoblastoma-associated protein B domain.
synonym: "RBL1/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000118 ! retinoblastoma-like protein 1

[Term]
id: PR:000000559
name: retinoblastoma-like protein 1 isoform 1 phosphorylated 1
def: "A retinoblastoma-like protein 1 isoform 1 phosphorylated form in which the phosphorylation occurs in an RxL motif-dependent fashion by cyclin Cdk4. Example: UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "RBL1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000458 ! retinoblastoma-like protein 1 isoform 1 phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000000304
name: retinoblastoma-like protein 1 isoform 2
def: "A retinoblastoma-like protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28749-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
comment: Category=sequence.
synonym: "RBL1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000118 ! retinoblastoma-like protein 1

[Term]
id: PR:Q24472
name: retinoblastoma family protein (fruit fly)
def: "A retinoblastoma-like protein 1 that is encoded in the genome of fruit fly." [PRO:CNA]
comment: Category=organism-gene.
synonym: "Rbf" RELATED Gene-based [UniProtKB:Q24472]
synonym: "CG7413" RELATED Gene-based [UniProtKB:Q24472]
synonym: "fly-RBL1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q24472
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000000118 ! retinoblastoma-like protein 1
relationship: has_gene_template FlyBase:FBgn0015799 ! Rbf (fruit fly)

[Term]
id: PR:000036470
name: retinoblastoma-like protein 1 isoform 1 phosphorylated 1 (human)
def: "A retinoblastoma-like protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046." [PMID:11884610, PRO:CNA]
comment: Category=organism-modification.
synonym: "hRBL1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P28749-1, Thr-369, MOD:00047|Ser-640/Ser-964/Ser-975, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000559 ! retinoblastoma-like protein 1 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:Q64701-1
name: retinoblastoma-like protein 1 isoform Long (mouse)
def: "A retinoblastoma-like protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mRBL1/iso:Long" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q64701-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000000303 ! retinoblastoma-like protein 1 isoform 1