[Term]
id: PR:Q08999
name: retinoblastoma-like protein 2 (human)
def: "A retinoblastoma-like protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q08999]
comment: Category=organism-gene.
synonym: "RB2" RELATED Gene-based [UniProtKB:Q08999]
synonym: "RBL2" RELATED Gene-based [UniProtKB:Q08999]
synonym: "hRBL2" EXACT PRO-short-label [PRO:DNx]
synonym: "p130 (human)" BROAD [UniProtKB:Q08999]
synonym: "pRb2 (human)" EXACT [UniProtKB:Q08999]
synonym: "RBR-2 (human)" EXACT [UniProtKB:Q08999]
synonym: "retinoblastoma-related protein 2 (human)" EXACT [UniProtKB:Q08999]
synonym: "130 kDa retinoblastoma-associated protein (human)" EXACT [UniProtKB:Q08999]
xref: Reactome:R-HSA-389102 "PR:Q08999 located_in GO:0005654"
xref: UniProtKB:Q08999
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000119 ! retinoblastoma-like protein 2
relationship: has_gene_template HGNC:9894 ! RBL2 (human)

[Term]
id: PR:Q08999-1
name: retinoblastoma-like protein 2 isoform 1 (human)
def: "A retinoblastoma-like protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "hRBL2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q08999-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000306 ! retinoblastoma-like protein 2 isoform 1

[Term]
id: PR:Q08999-2
name: retinoblastoma-like protein 2 isoform h2 (human)
def: "A retinoblastoma-like protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q08999-2." [PRO:DNx, UniProtKB:Q08999]
comment: Category=organism-sequence.
synonym: "hRBL2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q08999-2
is_a: PR:Q08999 ! retinoblastoma-like protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000000119
name: retinoblastoma-like protein 2
def: "A retinoblastoma-like protein that is a translation product of the human RBL2 gene or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=gene.
synonym: "RB2" RELATED Gene-based []
synonym: "RBL2" EXACT PRO-short-label [PRO:DNx]
synonym: "p130" BROAD [PRO:DNx]
synonym: "pRb2" EXACT []
synonym: "RBR-2" EXACT []
synonym: "retinoblastoma-related protein 2" EXACT []
synonym: "130 kDa retinoblastoma-associated protein" EXACT []
is_a: PR:000000023 ! retinoblastoma-like protein

[Term]
id: PR:000049025
name: retinoblastoma-like protein 2 phosphorylated 4 (human)
def: "A retinoblastoma-like protein 2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-401, and phosphoserine at positions 672 and 1035 of the amino acid sequence represented by UniProtKB:Q08999. UniProtKB:Q08999, Thr-401, MOD:00047|Ser-672/Ser-1035, MOD:00046." [PRO:DNx, Reactome:R-HSA-1226084]
comment: Category=organism-modification.
synonym: "hRBL2/Phos:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q08999, Thr-401, MOD:00047|Ser-672/Ser-1035, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1226084 "PR:000049025 located_in GO:0005654"
is_a: PR:Q08999 ! retinoblastoma-like protein 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000036471
name: retinoblastoma-like protein 2 isoform 1 phosphorylated 1 (human)
def: "A retinoblastoma-like protein 2 isoform 1 phosphorylated 1 in human. UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
comment: Category=organism-modification.
synonym: "hRBL2/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q08999-1, Thr-401/Thr-417/Thr-642/Thr-694/Thr-986/Thr-1097, MOD:00047|Ser-413/Ser-639/Ser-662/Ser-672/Ser-688/Ser-948/Ser-952/Ser-962/Ser-966/Ser-973/Ser-982/Ser-1035/Ser-1044/Ser-1068/Ser-1080/Ser-1112, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000560 ! retinoblastoma-like protein 2 isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000036472
name: retinoblastoma-like protein 2 isoform 1 phosphorylated 2 (human)
def: "A retinoblastoma-like protein 2 isoform 1 phosphorylated 2 in human. UniProtKB:Q08999-1, Ser-672, MOD:00046." [PMID:12006580, PRO:CNA]
comment: Category=organism-modification.
synonym: "hRBL2/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q08999-1, Ser-672, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000561 ! retinoblastoma-like protein 2 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000036473
name: retinoblastoma-like protein 2 isoform 1 phosphorylated 3 (human)
def: "A retinoblastoma-like protein 2 isoform 1 phosphorylated 3 in human. UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047." [PMID:11042701, PMID:11157749, PMID:8710362, PRO:CNA]
comment: Category=organism-modification.
synonym: "hRBL2/iso:1/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q08999-1, Ser-639/Ser-952/Ser-966/Ser-971/Ser-972/Ser-973/Ser-981/Ser-982, MOD:00046|Thr-974/Thr-986, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000000562 ! retinoblastoma-like protein 2 isoform 1 phosphorylated 3
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine