[Term] id: PR:000049280 name: mothers against decapentaplegic homolog 1 ubiquitinated form (human) def: "A mothers against decapentaplegic homolog 1 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q15797, MOD:01148." [PRO:DNx, Reactome:R-HSA-6782768] comment: Category=organism-modification. synonym: "hSMAD1/UbiqLys+" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q15797, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6782768 "PR:000049280 located_in GO:0005829" intersection_of: has_part MOD:01148 ! ubiquitinylated lysine intersection_of: PR:Q15797 ! mothers against decapentaplegic homolog 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q15797-2 name: mothers against decapentaplegic homolog 1 isoform h2 (human) def: "A mothers against decapentaplegic homolog 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15797-2." [PRO:DNx, UniProtKB:Q15797] comment: Category=organism-sequence. synonym: "hSMAD1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q15797-2 is_a: PR:Q15797 ! mothers against decapentaplegic homolog 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q15797-1 name: mothers against decapentaplegic homolog 1 isoform 1 (human) def: "A smad1 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hSMAD1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q15797-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000467 ! smad1 isoform 1 [Term] id: PR:000026334 name: smad1 isoform 1 phosphorylated 1 (human) def: "A smad1 isoform 1 phosphorylated 1 in human. UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046." [PRO:DAN, Reactome:R-HSA-201464, Reactome:R-HSA-201483] comment: Category=organism-modification. synonym: "hSMAD1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "phospho-R-smad1 (human)" EXACT [Reactome:R-HSA-201464] synonym: "UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000647 ! smad1 isoform 1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000000363 name: smad1 def: "A BMP receptor-regulated smad protein that is a translation product of the human SMAD1 gene or a 1:1 ortholog thereof." [PMID:10708949, PRO:CNA] comment: Category=gene. synonym: "BSP1" RELATED Gene-based [] synonym: "Mad1" EXACT [] synonym: "BSP-1" EXACT [] synonym: "Dwf-A" EXACT [] synonym: "JV4-1" EXACT [] synonym: "MADH1" RELATED Gene-based [] synonym: "MADR1" RELATED Gene-based [] synonym: "SMAD1" EXACT PRO-short-label [PRO:DNx] synonym: "SMAD 1" EXACT [] synonym: "dwarfin-A" EXACT [] synonym: "MAD homolog 1" EXACT [] synonym: "SMAD family member 1" EXACT [] synonym: "Mad-related protein 1" EXACT [] synonym: "mothers against DPP homolog 1" EXACT [] synonym: "mothers-against-DPP-related 1" EXACT [] synonym: "transforming growth factor-beta-signaling protein 1" EXACT [] is_a: PR:000000038 ! BMP receptor-regulated smad protein [Term] id: PR:Q15797 name: mothers against decapentaplegic homolog 1 (human) def: "A smad1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q15797] comment: Category=organism-gene. synonym: "BSP1" RELATED Gene-based [UniProtKB:Q15797] synonym: "MADH1" RELATED Gene-based [UniProtKB:Q15797] synonym: "MADR1" RELATED Gene-based [UniProtKB:Q15797] synonym: "SMAD1" RELATED Gene-based [UniProtKB:Q15797] synonym: "hSMAD1" EXACT PRO-short-label [PRO:DNx] synonym: "BSP-1 (human)" EXACT [UniProtKB:Q15797] synonym: "JV4-1 (human)" EXACT [UniProtKB:Q15797] synonym: "Smad1 (human)" EXACT [UniProtKB:Q15797] synonym: "SMAD 1 (human)" EXACT [UniProtKB:Q15797] synonym: "MAD homolog 1 (human)" EXACT [UniProtKB:Q15797] synonym: "SMAD family member 1 (human)" EXACT [UniProtKB:Q15797] synonym: "Mad-related protein 1 (human)" EXACT [UniProtKB:Q15797] synonym: "mothers against DPP homolog 1 (human)" EXACT [UniProtKB:Q15797] synonym: "transforming growth factor-beta-signaling protein 1 (human)" EXACT [UniProtKB:Q15797] xref: Reactome:R-HSA-201468 "PR:Q15797 located_in GO:0005829" xref: UniProtKB:Q15797 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000363 ! smad1 relationship: has_gene_template HGNC:6767 ! SMAD1 (human) [Term] id: PR:000036553 name: smad1 isoform 1 phosphorylated and ubiquitinated 1 (human) def: "A smad1 isoform 1 phosphorylated and ubiquitinated 1 in human. UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046|MOD:01148." [PMID:12857866, PRO:CNA, PRO:DAN] comment: Category=organism-modification. synonym: "hSMAD1/iso:1/PhosUbiq:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q15797-1, Ser-463/Ser-465, MOD:00046|MOD:01148" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000000648 ! smad1 isoform 1 phosphorylated and ubiquitinated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: has_part MOD:01148 ! ubiquitinylated lysine [Term] id: PR:000050147 name: smad1 phosphorylated 1 (human) def: "A smad1 phosphorylated 1 in human. UniProtKB:Q15797, Ser-463/Ser-465, MOD:00046." [PRO:DAN] comment: Category=organism-modification. synonym: "hSMAD1/Phos:1" EXACT PRO-short-label [PRO:DAN] synonym: "UniProtKB:Q15797, Ser-463/Ser-465, MOD:00046" EXACT PRO-proteoform-std [PRO:DAN] xref: Reactome:R-HSA-201464 "PR:000050147 located_in GO:0005829" xref: Reactome:R-HSA-201483 "PR:000050147 located_in GO:0005654" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000050148 ! smad1 phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine