[Term]
id: PR:000000655
name: smad2 isoform Short acetylated and phosphorylated 1
def: "A smad2 isoform Short acetylated and phosphorylated form in which the phosphorylation occurs at the last two Ser residues within the SSxS C-terminal motif by TGF-beta pathway activation and acetylated in a Lys residue within the MH1 domain by coactivators, such as CBP, PCAF and EP300. Example: UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756]
comment: Category=modification.
synonym: "SMAD2/iso:Short/AcPhos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000575 ! smad2 isoform Short acetylated and phosphorylated form
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine